Tumor Microenvironment 3D Cell Models to Address Therapeutic Response

Monday, 24 June 2024 at 15:30

Add to Calendar ▼2024-06-24 15:30:002024-06-24 16:30:00Europe/LondonTumor Microenvironment 3D Cell Models to Address Therapeutic ResponseOrganoids and Spheroids Europe 2024 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

The presentation will focus on the following topics:

  • Representation of the Tumor microenvironment (TME) is critical to study response to advanced therapeutics.
  • Different strategies to represent the TME, developed in the Lab will be presented, based on 3D cell culture models, namely:
  • Reconstruction modeling strategies, involving cancer cell line derived spheroids and non-malignant TME cellular components co-cultures (e.g., fibroblasts, macrophages).
  • Preservation modeling approaches employing patient-derived tumor tissue for translational and clinical research.

Giacomo Domenici, Associate Scientist, Instituto de Biologia Experimental e Tecnológica (iBET)

Giacomo Domenici

Giacomo Domenici holds a Ph.D. in molecular biology and biomedicine. Currently, he is an Associate Scientist at the Advanced Cell Models Lab led by Dr Catarina Brito at the Instituto de Biologia Experimental e Tecnológica (iBET). His current main research areas are: development and application of 3D cell models both for basic and applied cancer research, which have been employed in several research projects, also with pharmaceutical industry. His key areas of interest include cancer cell biology, the innate immunity response, the tumor microenvironment, immunotherapies, and the development of novel targeted therapies against cancer.