Chulhee Choi

Professor and Chair, BioMedical Imaging Center, Korea Advanced Institute of Science and Technology (KAIST), President, ILIAS Biologics Incorporated

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Chulhee Choi is Professor of Department of Bio and Brain Engineering at KAIST in South Korea. In addition, he is a scientific founder and CEO of ILIAS Biologics Incorporated, a company dedicated for development of exosome-based novel therapeutics. His group has been studying cell signaling involved in cell death and proliferation in inflammatory conditions and various malignant cancers. Dr. Choi’s group has also focused on development of novel biomedical imaging tools such as dynamic ICG fluorescence imaging for deep tissue perfusion and novel optical technology using femtosecond ultrashort pulsed lasers for modulation of biological functions. Recently, his team has demonstrated that optogenetic engineering of exosome producing cells can be applied for intracellular delivery of bioactive proteins with therapeutic potentials. His group is now pursuing research and development for clinically available exosome-based therapeutics. He is a graduate of Yonsei University College of Medicine, where he received his MD and PhD.

 

Hollis Cline

Chair of Neuroscience and Hahn Professor of Neuroscience, The Scripps Research Institute

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Hollis Cline, PhD, is the Hahn Professor of Neuroscience and co-chair of the Department of Neuroscience at Scripps Research in La Jolla, CA. She is a Councilor for the National Institute of Neurological Disorders and Stroke (NINDS), and has served on the council of the National Eye Institute (NEI) and on the Blue Ribbon Review Panel for the 10-year review of the National Institute of Child Health and Development (NICHD). Dr. Cline is a Fellow of the American Association for the Advancement of Science and has received the prestigious NIH Director’s Pioneer Award. Dr. Cline is a Past President of the Society for Neuroscience. She received her BA from Bryn Mawr College and her PhD from the University of California at Berkeley, followed by postdoctoral training at Yale University and Stanford University. She has served on the faculty of the University of Iowa and Cold Spring Harbor Laboratory, where she served as the Director of Research from 2002-2006. Dr. Cline’s research has demonstrated the roles of a variety of activity-dependent mechanisms in controlling structural plasticity of neuronal dendrites and axons, synaptic maturation and topographic map formation. This body of work has helped to generate a comprehensive understanding of the role of experience in shaping brain development. Two key points to emerge from her research is that circuit formation in vivo is a dynamic process throughout development that is continuously guided by experience, and that the basic mechanisms governing brain development, plasticity, information processing and organizational principles of brain circuits are highly conserved across vertebrates.

 

Jan Lötvall

Professor, University of Gothenburg; Founding President of ISEV; Editor-in-Chief, Journal of Extracellular Vesicles

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Jan Lötvall is Professor at the Institute of Medicine at Göteborg University since 2002 where he directs a research laboratory studying extracellular vesicles. He is a medical specialist in both Clinical Allergy and Clinical Pharmacology, and has a long-term experience in translational studies in primarily inflammation, but also cancer. He was first elected President of the International Society for Extracellular Vesicles (ISEV, 2011-2016), a rapidly growing non-profit organisation in the field of exosomes, microvesicles and other extracellular vesicles (www.isev.org; >1100 members). The research line focusing on extracellular vesicle biology has received extensive international recognition, as the lab was first to discover the ability of exosomes to shuttle RNA between cells in 2007. During the period of May 2016 to January 2018, JL served as Chief Scientist at Codiak BioSciences, a startup biotech company focusing on developing exosomes as a therapeutic platform. From January 2018, JL was the founding editor of the journals “Clinical and Translational Allergy” (2011, IF 3.239) and Journal of Extracellular Vesicles (JEV: IF 14.9). JL is the current Editor-in-Chief of JEV since August 2019. He is also the Chief Executive Officer and Chief Scientific Officer of Exocure Biosciences, a privately held vesicle therapeutics company.

 

Dominique PV de Kleijn

Professor Experimental Vascular Surgery, Professor Netherlands Heart Institute, University Medical Center Utrecht, The Netherlands

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Prof. Dr. Dominique PV de Kleijn is molecular biologist and chemist and professor of Exp. Vascular Surgery at UMC Utrecht and professor at the Netherlands Heart Institute. From 2012 to 2016, he was Research Professor of Surgery at NUS/NUHS and preclinical director of the Cardiovascular Research Institute (CVRI) Singapore. He was until 2016 professor of Cardiovascular Immunology and co-chair of Experimental Cardiology at UMC Utrecht. Since 1997 he is coordinating cardiovascular research from basic science, animal myocardial infarction and atherosclerotic studies (pig and sheep) towards clinical biobanking studies. His research interests are: The innate immune system in cardiovascular disease and atherosclerosis & Biomarkers predictive for primary & secondary events with a focus on plasma extracellular vesicles. He has more then 275 publications and a H-factor of 78.