Stephen Beers

Professor of Immunology and Immunotherapy, University of Southampton

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Stephen Beers is Professor of Immunology and Immunotherapy at the Centre for Cancer Immunology, University of Southampton. He leads a research group studying antibody drugs and their mechanisms of action. The group’s research is currently focussed on two main areas: 1) the mechanisms of action of immunomodulatory mAb, and 2) how the tumour microenvironment affects antibody effector function and how this might be manipulated to enhance patient outcomes. Their work utilises a portfolio of complimentary models incorporating in vitro 3D modelling, appropriate in vivo model systems and primary clinical material.

 

Sara Colombetti

Global Head Oncology Discovery Pharmacology, pharma Research and Early Development (pRED), Roche Innovation Center Zürich

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I have received my Ph.D. in Molecular and Cellular biology at the San Raffaele Scientific Institute in Milan (Italy). After a post-doc in cancer immunotherapy at the Ludwig Institute for Cancer Research (Lausanne branch) and later at Cytos Biotechnology (Zurich), I have joined the Roche Innovation Center Zurich in 2009. There I have led first the preclinical in vivo models group, then the Immuno-pharmacodynamics and Bioanalytics group and have been appointed as global Head of the Oncology Discovery Pharmacology Department in 2018.

 

Elena Menietti

Scientist, Oncology Discovery Pharmacology, pharma Research and Early Development (pRED), Roche Innovation Center Zürich

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Elena Menietti received her Ph.D. in Cancer and Immunology at the University of Lausanne, Switzerland, in 2016. She then joined Roche Oncology Discovery Pharmacology for her post-doctoral studies in the Pre-clinical Imaging group, and was appointed scientist in the Pre-clinical Imaging and Histology group. She is in charge of developing new imaging tools to explore the tumor microenvironment in response to cancer immuno-therapy.

 

Graham Pockley

Director and Professor, John van Geest Cancer Research Centre, Nottingham Trent University, CEO, multimmune GmbH

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Professor A. Graham Pockley, PhD is the CEO of multimmune GmbH (www.multimmune.com), Munich, Germany. multimmune’s unique and proprietary technology platform is based on the discovery (by Gabriele Multhoff and Claus Botzler) that a cell surface bound form of Hp70 is selectively and widely expressed on the plasma membranes of many tumour entities. multimmune is developing innovative theranostics on the basis of membrane Hsp70 expression by tumour cells, including an autologous NK cell-based therapy (ENKASTIMev)

Graham Pockley is also Professor of Immunobiology and Director of the John van Geest Cancer Research Centre (JvGCRC) at Nottingham Trent University, Nottingham, UK. The JvGCRC uses integrated genomic, proteomic, immunological and bioinformatics platforms to identify biomarkers of disease and disease progression, predict therapeutic responses and develop diagnostic and immunotherapeutics. Programmes study the orchestration of innate and adaptive immunity in cancer, discover immunological and protein biomarkers of disease and therapeutic responses in cancer, and its findings inform the development and delivery of new diagnostic and immunotherapeutic strategies.

 

Ed Schuuring

Professor in Molecular Oncological Pathology, University Medical Center Groningen

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Prof Dr Ed Schuuring, PhD, senior clinical scientist in molecular pathology, University Medical Center Groningen, Groningen, The Netherlands

He finished his graduate training in Medical Biology in 1985 (cum laude) and PhD in 1993 in Molecular Biology at the Netherlands Cancer Institute (University of Amsterdam). In 1991 he received a staff position at the department of Pathology of LUMC in Leiden with focus on the identification of diagnostic relevant and predictive molecular markers for clinical outcome in breast cancer and BNHL lymphoma, and coordinated the introduction of molecular diagnostic pathology. In 2001 he moved to the department of Pathology of the UMCG in Groningen. His research focuses on the identification of prognostic/predictive epigenetic and molecular markers for clinical outcome, response to (chemo) radiotherapy, gene-targeted therapy and treatment-resistance in lung and head&neck cancer, as well as for the early detection of cervical cancer in scrapings. He was/is (co-) project leader on >31 research projects (ZONMW-COIN, ZONMW-PATH, NKB-KWF) and (co-) author of > 220 papers in peer-reviewed journals.

In addition to research, he is heading the laboratory of molecular pathology at UMCG for the region North-Netherlands. Since 1997 he is active in (inter)national committees and advisory boards on implementing molecular diagnostic pathology and active member in External Quality Assessment (Euroclonality, SKML, ESP, QCMD, IQNPath) by organizing international proficiency testing for mutations in EGFR, ALK, KRAS, ROS, MET and HPV in tissue biopsies and ctDNA from blood plasma. He is co-author on various international guidelines in Molecular Pathology. In October 2011 he was appointed full professor in “Molecular Oncological Pathology” and in July 2013 registered as Clinical Scientist in Molecular Pathology (KMBP) by the Dutch Society for Pathology. He has several collaborations with biotech companies in clinical trials or to develop companion diagnostics (Abbott, BMS, Biocartis, Roche, Hologic, Boeringer Ingelheim, CC Diagnostics). He acts regular upon invitation of companies as consultant, advisor or speaker regarding new development in molecular diagnostics (e.g. Amgen, Abbott, Astrazeneca, BMS, Bayer, Illumina, Biocartis, Novartis, Roche, Pfizer). He is member of the Dutch Society of Pathology (president of the section Clinical, Molecular and Experimental Pathology), American Association of Cancer Research, Dutch Society of Oncology, American Society of Clinical Oncology, European Society of Pathology and Association of Molecular Pathology.

Please find more details on my research and publications on http://www.rug.nl/staff/e.m.d.schuuring/ and information on Molecular Pathology on www.moloncopath.nl and www.pathology.nl