Martyn Boutelle

Professor of Biomedical Sensors Engineering, Imperial College London

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Martyn Boutelle is Professor of Biomedical Sensors Engineering in the Department of Bioengineering, Imperial College London, and Associate Provost for Estates Planning for Imperial College.
His research group is multidisciplinary comprising, bioengineers, scientists, and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors / biosensors, and wireless electronics to make portable (sometimes wearable) monitoring devices for use as point of care devices that typically giving continuous real -time displays. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury including that caused by cardiac arrest, neonatal continuous monitoring and kidney transplantation monitoring. He runs the EPSRC funded Bio-nanofabrication suite designed to make microfluidic and biosensor biosensors using scalable methods to allow use in proof-of-concept clinical trials.

Martyn is past president of the International Society for Monitoring Molecules in Neuroscience, and a founder of the COSBID organization for studying acute human brain injury. He published > 190 papers, chapters and patents. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.

 

John Brennan

Professor and Director, Biointerfaces Institute, McMaster University

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Professor John Brennan holds the Canada Research Chair in Bioanalytical Chemistry and Biointerfaces (Tier 1) and is Director of the Biointerfaces Institute at McMaster University. He is an expert in the development of biosensors and point-of-care diagnostics, with specific expertise in bioactive paper, high-throughput development of printable biomaterials, and development of solid-phase assays for diagnostics and small molecule screening. Dr. Brennan has published over 200 peer-reviewed papers, given over 150 invited presentations, and has been awarded several patents in the areas of POC diagnostics.

 

Hsueh-Chia Chang

Bayer Professor of Chemical and Biomolecular Engineering, University of Notre Dame, Interim Chief Technology Officer, Aopia Biosciences

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Over 300 publications, with 18,000 citations and h index of 76. He has confounded a startup Aopia Biosciences in 2020 on purification of extracellular vesicles and currently serves as its interim CTO.

 

Dino Di Carlo

Armond and Elena Hairapetian Chair in Engineering and Medicine, Professor and Vice Chair of Bioengineering, University of California-Los Angeles

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Dino Di Carlo received his B.S. in Bioengineering from the University of California, Berkeley in 2002 and received a Ph.D. in Bioengineering from the University of California, Berkeley and San Francisco in 2006. From 2006-2008 he conducted postdoctoral studies in the Center for Engineering in Medicine at Harvard Medical School. He has been on the faculty in the Department of Bioengineering at UCLA since 2008 and now as Professor of Bioengineering and Mechanical Engineering serves as the Vice Chair of the Department and as the director of the Cancer Nanotechnology Program in the Jonsson Comprehensive Cancer Center. His research pioneered the use of inertial fluid dynamic effects for the control, separation, and analysis of cells in microfluidic devices. His recent work extends into numerous other fields of biomedicine and biotechnology including directed evolution, cell analysis for rapid diagnostics, new amplified molecular assays, next generation biomaterials, and phenotypic drug screening. He has also been a leader in technology entrepreneurship: He co-founded and currently serves on the board of directors of five companies that are commercializing UCLA intellectual property developed in his lab (CytoVale, Vortex Biosciences, Tempo Therapeutics, Forcyte Biotechnologies and Ferrologix). Among other honors he received the Presidential Early Career Award for Scientists and Engineers (PECASE) and was elected a Fellow of the American Institute for Medical and Biological Engineering in 2016, was elected a Fellow of the Royal Society of Chemistry (FRSC) in 2014, was awarded the National Science Foundation (NSF) Faculty Early Career Development award and the U.S. Office of Naval Research (ONR) Young Investigator Award, the Packard Fellowship and Defense Advanced Research Projects Agency (DARPA) Young Faculty Award, and received the National Institutes of Health (NIH) Director’s New Innovator Award and Coulter Translational Research Award.

 

Michael Heller

Professor, Dept Bioengineering, University of California-San Diego

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Michael J. Heller received his PhD in Biochemistry from Colorado State University in 1973. He was an NIH Postdoctoral Fellow at Northwestern University from 1973 to 1976. From 1976 to 1984 he was supervisor of the DNA Technology Group at Amoco Corporation (Standard Oil Indiana) During that time he carried out early bioengineering and recombinant DNA work on plants, algae and photosynthetic bacteria for energy and chemical production, and developed some of the first fluorescent resonant energy transfer (FRET) and chemiluminescent oligonucleotide probes for DNA hybridization analysis. He also oversaw Amoco’s sponsored energy and chemical research work at Cetus Corporation, which included the cloning of thermophilic enzymes. Dr. Heller was the Director of Molecular Biology at Molecular Biosystems, Inc., from 1984 to 1987. He was a co-founder of Integrated DNA Technologies, and served as President and Chief Operating Officer from 1987 to 1989. He was a co-found of Nanogen and served as the Chief Technical Officer from 1993 to 2001. Nanogen carried out the successful development and commercialization of electronic DNA microarray technology for clinical diagnostic genotyping applications. Dr. Heller is a Professor (Recall/Emeritus) in the Departments of Nanoengineering and Bioengineering at the University California San Diego. He is also now a Distinguished Scientist at the Oregon Health & Science University (OHSU), Center for Cancer Early Detection and Research (CEDAR), in Portland, Oregon. He has also co-founded a company called Biological Dynamics which is developing new sample to answer cancer diagnostics technology, based on the novel dielectrophoretic (DEP) technology developed at his UCSD lab. Dr. Heller has extensive industrial experience in biotechnology, biomedical and molecular diagnostic devices and nanotechnology, with particular expertise in the areas of DNA probe diagnostics, electrokinetic lab-on-a-chip devices, DNA synthesis, FRET/fluorescent-based detection technologies and electric field assisted self-assembly of DNA nanostructures. Dr. Heller has over 100 publications and 56 issued US patents.

 

Chwee Teck Lim

NUS Society Chair Professor, Department of Biomedical Engineering, Institute for Health Innovation & Technology (iHealthtech), Mechanobiology Institute, National University of Singapore

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Professor Chwee Teck LIM is the NUS Society Chair Professor of Biomedical Engineering and Director of the Institute for Health Innovation and Technology at the National University of Singapore. His research interest is in the development of microfluidic technologies for applications in disease diagnosis and health monitoring. He has co-authored over 470 journal publications and is also a serial entrepreneur having started six companies. Prof Lim is an Elected Fellow of seven academies including the US National Academy of Inventors, IUPESM, AIMBE, IAMBE, AAET, among others. He and his team have garnered numerous research awards and honours including Asia’s Most Influential Scientist, Highly Cited Researcher, Asian Scientists 100, Wall Street Journal Asian Innovation Award (Gold) and the President's Technology Award among others.

 

Arben Merkoçi

ICREA Professor and Director of the Nanobioelectronics & Biosensors Group, Institut Català de Nanociencia i Nanotecnologia (ICN2), Barcelona Institute of Science and Technology (BIST)

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Arben Merkoçi is currently ICREA Professor and director of the Nanobioelectronics & Biosensors Group at Institut Català de Nanociencia i Nanotecnologia (ICN2), part of Barcelona Institute of Science and Technology (BIST). After his PhD (1991) at Tirana University (Albania), in the topic of Ion-Selective-Electrodes (ISEs) Dr. Merkoçi worked as postdoc and senior researcher/invited professor in the field of nanobiosensors and lab-on-a-chip technologies in Italy, Spain, USA and since 2006 at ICN2. Prof. Merkoçi research is focused on the design and application of cutting edge nanotechnology and nanoscience based cost/efficient biosensors. The paper/plastic-based nanobiosensors involve integration of biological molecules (DNA, antibodies, cells and enzymes) and other (bio)receptors with micro- and nanostructures/motors and applied in diagnostics, environmental monitoring or safety and security. He has published around 300 peer review research papers (H index: 61 WOS; 79 GS), supervised 30 PhD students and has been invited to give plenary lectures and keynote speeches in around 200 occasions in various countries. Prof. Merkoçi is Co-Editor In Chief of Biosensors and Bioelectronics and member of Editorial Board of other journals. He is co-founder of two spin-off companies, PaperDrop dedicated to nanodiagnostics and GraphenicaLab to electronic printing. See more details on his CV at: https://www.icrea.cat/security/files/researchers/files-maintenance/full_cv_amerkoci_0.pdf

 

Steve Soper

Foundation Distinguished Professor, Director, Center of BioModular Multi-Scale System for Precision Medicine, The University of Kansas

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Prof. Soper is currently a Foundation Distinguished Professor in Chemistry and Mechanical Engineering at the University of Kansas, Lawrence. Prof. Soper also holds an appointment at Ulsan National Institute of Science and Technology in Ulsan, South Korea, where he is a World Class University Professor. He is also serving as a Science Advisor for a number of major worldwide companies. Prof. Soper is currently on the Editorial Board for Scientific Reports and Journal of Micro- and Nanosystems.

As a result of his efforts, Prof. Soper has secured extramural funding totaling >$103M and has published over 265 peer-reviewed manuscripts (h index = 71) and is the author of 20 patents. He is also the founder of a startup company, BioFluidica, which is marketing devices for the isolation and enumeration of circulating tumor cells. His list of awards includes Chemical Instrumentation by the American Chemical Society, the Benedetti-Pichler Award for Microchemistry, Fellow of the AAAS, Fellow of Applied Spectroscopy, Fellow of the Royal Society of Chemistry, R&D 100 Award, Distinguished Masters Award at LSU and Outstanding Scientist/Engineer in the state of Louisiana in 2001. Finally, Prof. Soper has granted 60 PhDs and 6 MS degrees to students under his mentorship. He currently heads a group of 20 researchers.

 

Bernhard Weigl

Director, Center for In-Vitro Diagnostics, Intellectual Ventures/Global Good-Bill Gates Venture Fund

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Dr. Bernhard H Weigl is the Director of the Center for In-Vitro Diagnostics at Intellectual Ventures/Global Good (IV/GG) and an Affiliate Professor at the University of Washington, Department of Bioengineering. The Global Good unit of Intellectual Ventures is directly funded by Bill Gates.

At IV/GG Dr. Weigl leads work to develop the next generation of highly sensitive diagnostic assays for diseases of relevance in developing countries, including TB, cervical cancer, and malaria. His team has recently demonstrated the most sensitive rapid assay for malaria to date. Previously he led the PATH Diagnostics Group where he oversaw global health diagnostics programs funded by a variety of sources such as NIAID and NIBIB, the Grand Challenges program of the Bill and Melinda Gates Foundation, USAID, and the PATH Health Innovation Portfolio. He also served as Portfolio Leader for Non-Communicable Disease Diagnostics and as Director of the National Institutes of Health-funded Center for Point-of-Care Diagnostics for Global Health. His current work focuses on diagnostic technology R&D with relevance to Global Health applications including ultra-sensitive strip-based immunoassays, molecular assays in cartridge and digital formats, novel assay formats, and other biotechnology research for low resource settings.

Before joining PATH, both at the University of Washington and at Micronics, Inc. (Redmond, Washington, now a wholly owned subsidiary of Sony Corporation of America) where he was a scientific cofounder), Dr. Weigl led teams that developed both instrument-based and stand-alone microfluidic medical diagnostic disposables, including the first FDA-approved instrument-free microfluidic test, the ABORhCard®.
His scientific interests include traditional and paper-based microfluidics as well as any assay platform that allows simplification and integration of previously complex assays. As chronic diseases, and especially diabetes, are emerging as a major health threat in developing countries he is now also focusing on their diagnosis, screening, and treatment. Other areas of interest include diagnostics-related health systems topics such as more rational diagnostic algorithms, and evaluation and selection of the most appropriate diagnostic tool for a particular application using metrics beyond sensitivity and specificity. He has led projects across the diagnostics value chain, from invention and proof of principle though product introduction and support.

He received his M.Sc (Mag. rer. nat.) and Ph.D. (Dr. rer. nat.) from Karl-Franzens-University Graz and has completed post-doctoral studies at the University of Southampton and the University of Washington. He has authored more than 130 scientific publications and is an inventor on over 80 US patents and published patent applications.