Drug Discovery Technology: Uncovering the Molecular Interactions

Held in conjunction with Drug Discovery India 2013

29 Sep 2013, at 10:00 am-5:00 pm in Banglore, India

Genomics, Proteomics, Virtual Screening, Molecular Docking, Simulations & Dynamics, ADMET studies, has brought a revolution in the field of Drug Discovery & Designing. With the challenges that are faced by the drug industry today, drug development teams require a specific combination of skills to ensure they stay abreast of scientific advancements and are at the forefront of the market.

WHO SHOULD ATTEND

The course is suitable for students, researchers, faculty, lecturers, scientists, technicians, engineers, academicians and company professionals from Biotechnology/Bioinformatics/Pharma/Veterinary background.

COURSE CONTENTS

• The topics which will be covered in this training include:
• Introduction of Drug Designing
• Science involved in disease target identification
• Virtual screening

Apart from above elementary topics the training & practical application will be given for following topics:
• In-silico generation of ligands
• Protein optimization & energy minimization
• Molecular Docking
• Creation of Grid Paramater & Dock Parameter files.
• Running the Docking Algorithm
• Selection of potent inhibitors based upon binding energies & Lipinski’s Rule of 5
• Look for H-bond between ligand and active site of the residue of protein.
• Analysis and Evaluation

Practical application will be done on 5-10 molecules and the software on which training will be given:
• ChemSketch- Drawing the molecules- In-silico generation of ligands.
• Open Babel- Conversion of one file format to other.
• MGL Tools- Lamarckian Genetic Algorithm- Docking.
• Cygwin- Running the algorithm.
• UCSF Chimera- Structure Analysis. H-Bond interaction.
• Online software for Drug Likeness & ADMET.

Note: Service tax @ 12.36% is applicable at all the prices mentioned above.