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Held in conjunction with Lab-on-a-Chip and Microfluidics Europe 2020
08 Sep 2020, at 12:00-14:30 in Rotterdam, The Netherlands
Venue of the Training Course: Rijndam Room - 7th Floor - Marriott Rotterdam, Rotterdam, The Netherlands.
SelectBIO is delighted to welcome you to the Principles and Applications of Microfluidics for Analytical Sciences Training Course presented by Professor Nicole Pamme. This course provides a deep-dive into contemporary topics in Lab-on-a-Chip and Microfluidics and is a perfect complement to the topics and content presented at the SelectBIO Lab-on-a-Chip and Microfluidics Europe 2020 Conference. Topics and Course Organization
Principles of Microfluidics and Construction of microTAS
- Benefits of miniaturizing fluid handling
- Challenges for bioanalysis today and how they can be addressed by lab-on-a-chip technology
Fabrication of Microfluidic Devices
- Overview of materials, fabrication processes and interfacing strategies
Flow behavior in microchannels
- Laminar and turbulent flow, diffusion, multi-phase flow with example applications
Handling of fluids
- Components for fluid handling including pumps, mixers and valves
Detection in microfluidic devices
- Suitable detection methods at the microscale including spectroscopy and electrochemical methods
Applications of Microfluidic Devices in Bioanalysis- DNA analysis
- On-chip DNA extraction, PCR and separation as well as hybridisation assays; case study: forensic DNA analysis
- Protein analysis
- On-chip immunoassays, lateral flow assays, pre-concentration, separation; case study: point–of-care analysis of cardiac markers
- Cell and tissue analysis
- Handling of single cells and cell arrays, analysis with living tissue slices, handling of living organisms
- Case study: organs-on-chip and human-on-a-chip to replace animal testing
- Integrated devices for point-of-care or in-the-field analysis
- Focus on microfluidic devices for point-of-care applications
Learning Objectives
- Understand the benefits and limitations of miniaturization and learn how lab-on-a-chip devices can be fabricated, assembled and operated
- Understand the behavior of fluids in microchannels and learn how this has led to methods of pumping, mixing and detection that can be quite different from those used on the larger scale
- Gain a broad overview over the applications of lab-on-a-chip devices in the area of environmental and life sciences including biomarker diagnostics, approaches to DNA and protein analysis as well as flow cells for cell and tissue analysis
- Understand the challenges towards integrated and portable analysis systems that can be used at the point-of-care for medical applications, at-the-scene for forensic applications or in-the-field for environmental applications, sometimes in resource limited settings
Who Should Attend?
This ‘crash-course’ is aimed at professionals, students, scientists, technicians and engineers who would like to learn (more) about lab-on-a-chip devices and their applications in the area of environmental and life sciences. Researchers who are interested in working with microfluidic devices will acquire a comprehensive overview of the field. The course will also provide an opportunity for researchers who already have experience with microfluidic devices but who would like to update or broaden their knowledge on recent developments in bio-applications.
Lunch is included for the attendees of this training course and all the presentation slide decks will be available for the course attendees.
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 Nicole Pamme, Professor in Analytical Chemistry, Stockholm University
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