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Held in conjunction with European Lab Automation
29 May 2012, at 13:30-17:00 in Hamburg, Germany
Who Should Attend? The course is suitable for scientists, technicians, engineers, quality control workers, students and lab managers who would like to learn (more) about usage of automated liquid handing in certified, accredited or forensic environments. This course presents an introduction to the process of standardizing, validating and accrediting automated liquid handling instruments and processes in both conventional and forensic environments.
Learning Objectives
1. Understand the benefits and challenges of working with automated liquid handlers in a certified or accredited environment. 2. Understand the challenges of standardization, validation and accreditation 3. Develop an understanding of the validation process 4. Learn to plan and execute implementation and validation of automated liquid handlers and processes 5. Understand the pitfalls of automated liquid handling in accredited or forensic environments and how to avoid with them.
Topics and Course Organization Understanding of Automated liquid handling systems 1. Introduction to Laboratory Automation Benefits of laboratory automation Downsides of laboratory automation 2. Automation options What could be automated? What should be automated? How should automation be introduced in an accredited lab? 3. Choice of liquid handler One large multipurpose instrument vs. several smaller dedicated instruments Open vs. closed systems Fixed tips vs. disposable tips Automated liquid handling in accredited or forensic environments 1. Validation Introduction to accreditation Validation of automated systems Validation of methods/scripts Testing and validation of pipetting performance 2. Script design Process flow Deck/worktable layout Reuse of sub-routines or loops 3. Volume verification of liquid handlers Do-it-yourself solutions Commercial solutions 4. Maintaining a validated process – validated Shared components of the validated scripts such as worktable/deck, pipetting techniques and liquid classes Common errors – and how to prevent them 5. Instrument Software and script upgrades Requirements from the standard ISO 17025 Instrument software variability How should software updates be handled – the process Firmware Test requirements
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