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SELECTBIO Conferences Advances in Genomics, Informatics and Bioanalysis

Advances in Genomics, Informatics and Bioanalysis Agenda

Co-Located Conference Agendas

Flow Chemistry India | 

Other Track Agendas

Advances in Genomics, Informatics and Bioanalysis | Drug Discovery & Development | 

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Tuesday, 30 October 2012


Genome-wide Analyses Reveals Novel Pancreatic Cancer Genes
Murali Bashyam, Scientist, Centre for DNA Fingerprinting and Diagnostics, India

The first part of the presentation shall highlight the use of several genome-wide approaches to identify putative important pancreatic cancer 'driver' genes, followed by a description of characterization of the 'drivers' using various approaches.


Frequency of JAK2 Exon 12 Mutations in Patients With JAK2 (V617F)-negative Myeloproliferative Disorders
Shefali Desai, Chief, iGenetic Diagnostics, India

JAK2 exon 12 mutation status is associated with erythrocytosis and atypical bone marrow morphology. Patients who test negative for JAK2V617F mutation should be tested for these mutations to classify further or rule out PV using allele-specific polymerase chain reaction (PCR) and sequencing. 


Lunch and Networking in the Exhibition Hall


Poster Viewing Session


Ravi SirdeshmukhKeynote Presentation

Tumor Associated Gene and Protein Expression Changes: Integrated Approaches to Study Glioblastoma and Other Tumors
Ravi Sirdeshmukh, Distinguished Scientist & Associate Director , Institute of Bioinformatics, India


Bioinformatics: Next-Generation Sequencing Data Analysis
Vivek Keshri, Research Associate, National Bureau of Agriculturally Important Microorganisms, India

Here, we present comparative genomics and its impact, next-generation sequencing data analysis for genome comparisons and basic approaches for the data analysis form of alignment, assembly, base calling, Chip-Seq, RNA-Seq, visualization tools and techniques.


Coffee Break and Networking in the Exhibition Hall


Characterization of a Novel Moonlighting Histone H3 Specific Protease Activity by a Known NAD+ Dependent Dehydrogenase From Chicken Liver
Jogeswar Purohit, Assistant Professor, Smt. C.H.M. College, India

Site-specific proteolysis of the N or C-terminus of histone tails has recently emerged as a novel form of irreversible post-translational modifications assigned to histones. In the present study liver specific proteolysis of histone H3 in adult chicken liver tissue is demonstrated. The proteolysis removes 23 amino acids from the N-terminus of histone H3. We further demonstrate a histone H3 specific protease (H3ase) activity in the chicken liver nuclear extract. H3ase was purified to homogeneity 


Hakim DjaballahKeynote Presentation

An Arrayed shRNA Genomewide RNAi Screen against Dengue Reveals Common Host-Virus Gene Signatures: Implications in Anti-Viral Drug Discovery and Re-purposing”
Hakim Djaballah, CEO, Institute Pasteur - Korea, Korea South

I will describe the execution of a virus-host interaction RNAi screen for Dengue against an arrayed lentiviral enabled shRNA library with two readouts assessing viral infection and host viability. The resulting targets offer a new opportunity for antiviral drug discovery through repurposing existing molecules.

Wednesday, 31 October 2012

Protein and Antibody Arrays Continued


Indigenous Development of Membrane Based BioChip Cassette and Biochip Arrayer System for Making Protein Microarrays
Ratnesh Sengar, Scientific Officer, Bhabha Atomic Research Centre, India

Indigenous development of a bio-chip cassette and arrayer system for producing the antibody based bio-chip for in vitro simultaneous quantitative detection of a combination of thyroid related hormones using polycarbonate (PC) track-etched membranes (TEM) as a novel substrate.

Liquid Chromatography and Mass Spectrometry


Peter HorvatovichKeynote Presentation

Bioinformatics Aspect of Label-Free LC-MS Comprehensive Profiling Technology
Peter Horvatovich, Assistant Professor, University of Groningen, Netherlands

Overview on current state-of-art and challenges of data processing methods for label-free LC-MS comprehensive profiling technology of complex biological samples.


Qualitative and Quantitative Analysis of Bioactive Alkaloides in Berberis and Mahonia Roots and use of PCA for Marker Identification for Quality Control.
Brijesh Kumar, Senior Principal Scientist, Central Drug Research Institute, India

The DART/Q-TOF/4000Qtrap LCMS techniques have been applied for the profiling of alkaloids in Berberis and Mahonia species. Chemical profiling of leaf, stem and root has been done successfully. PCA analysis has shown that DARTMS data can be used to differentiate these alkaloids containing plant species. This will help in identification of plants used for drug preparation and for the effective quality control in future.


Coffee Break & Networking in Exhibition Hall


Advances in Metabolite ID Strategies Using Hyphenated LC-MSMS Techniques
Umesh Pawa, Managing Director, AB Sciex, United Arab Emirates

A talk elaborating strategies and  workflows for simultaneous Metabolite Identification and quantitation using hyphenated LC-MS/MS technologies and novel scan modes in current day instrumentation.

Applications of Spectroscopy


Ethyl Glucuronide as a Biomarker of Alcohol Abuse
Bharat Venkatesh, Junior Scientific Officer, National Institute of Mental Health and Neurosciences, India

Sensitive and reliable analytical GC-MS method for determination of EtG in urine and serum was developed and validated. The performance of this method is sufficient to measure low EtG concentartion in both matrices. 


Lunch & Networking in Exhibition Hall


Poster Viewing Session


Rainer CramerKeynote Presentation

Automated Sample Preparation for MALDI MS Analysis in Clinical Proteomics
Rainer Cramer, Professor, University of Reading :(, United Kingdom

Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the two main ionization techniques in biological MS.  Its advantages are easy off-line sample preparation, high tolerance to contaminants and additives, and high speed analysis.  These properties are highly desirable for automated large-scale clinical proteomic analysis.  Thus, MALDI MS has already been used extensively in areas such as biomarker screening and discovery, biotyping of bacteria and other disease microbes, as well as imaging of clinical specimens.

This talk will provide an introduction into MALDI and its potential for clinical analysis, and an overview and future outlook of its application in large-scale automated clinical proteomics.


Coffee Break & Networking in Exhibition Hall

Advances in Biotechnology


Immunogenicity and Pharmacokinetics Assessment of Protein Biotherapeutics: An Overview
Mallikarjun Dixit, Laboratory Director, Clinigene International Ltd, India

With the advent of Biotechnology, more and more drug products currently available in the market are biotech derived human recombinant protein biotherapeutics which have replaced the animal derived drug products. This has helped in global availability of quality drug products at a competitive price with very little or nil side effects. To utilize the growing demand for the biotechnology derived drug products, many multinational agencies have established the biopharmaceutical units in different parts of the world using Recombinant DNA technology.


Close of Conference

Add to Calendar ▼2012-10-30 00:00:002012-10-31 00:00:00Europe/LondonAdvances in Genomics, Informatics and