Tuesday, 22 November 201108:00 | Registration | 10:30 | Coffee Break and Networking in Exhibition Hall | | Session: Molecular Diagnostics for Cancer |
| | 11:15 | Epigenetic Classification of ER-negative Primary Breast Cancer is Prognostic of Long-term Disease Outcome David Hoon, Professor, Director Department of Translational Molecular Medicine, John Wayne Cancer Institute, United States of America
The study describes the epigenetic subclassification of primary breast cancer. The focus is on ER-negative breast cancer which is difficult to manage and identify long-term disease outcome. The study is important for identifying better patient classification. | 11:45 |  | Keynote Presentation Applied Molecular Diagnostics in Solid Tumours: Past, Present and Future Brendan Pang, Director of the Diagnostic Molecular Oncology Centre, National University of Singapore, United Kingdom
This lecture provides a broad overview of applied molecular diagnostics and attempts to relate the diagnostic trends of today with tomorrow’s vision of identifying mutations and gene expression changes to reverse engineer oncogenic pathways and attempt virtual therapeutic simulations. |
| 12:15 | Lunch and Networking in Exhibition Hall | 13:30 | Poster Viewing Session | | Session: Molecular Diagnostics for Infectious Diseases |
| | 14:45 | Single-tube and Spatially Multiplexed Assay Formats for Detection of Pathogens, Mutations, SNPs, InDels, and RNA Manohar Furtado, VP, Life Technologies Corporation, United States of America
The presentation will describe several methods for detection and quantification of multiple nucleic acid targets that can aid in disease research. | 15:15 | Coffee and Networking in Exhibition Hall | 16:00 | Medium Throughput Real-time PCR for Multiplex Detection Qingge Li, Professor, Xiamen University, China
This presentation will discuss how real-time PCR can detect more than 10, 20 and even 40 different targets starting from a single reaction and its application in various areas. | 16:30 | Molecular Identification of Pathogenic Molds in the Environment by an Oligonucleotide Array Tsung Chang, Professor, National Cheng Kung University, Taiwan
Identification of molds is time-consuming and expertise-demanding. The current study developed an oligonucleotide array that could accurately identify 21 species of fungi that have a potential to cause infections in human. The array is rapid, cheap and accurate. | 17:00 | Drinks Reception |
Wednesday, 23 November 2011 | Session: Trends in Molecular Diagnostics |
| | 09:00 | QF-PCR as a Rapid Technique for Routine Prenatak Diagnosis of Fetal Aneuploidies Shereen Atef, Professor of Medicine, Ain Shams University, Egypt
Errors in meiosis result in gametes that contain abnormal numbers of chromosomes and produce aneuploidies. In the early 1990s, QF-PCR as a one of the molecular biological methods started to be used for the detection of major chromosomal aneuploidies aiming to provide rapid diagnosis. Nowadays QF –PCR has been confirmed to be highly sensitive and specific in detection of major chromosomal abnormalities, having the major advantage of high throughput of samples at low cost. | 09:30 | Adipose Stem Cell System as Potential Therapeutic Platforms for Metabolic Diseases Shigeki Sugii, Group Leader/Assistant Professor, Singapore Bioimaging Consortium/Duke NUS Graduate Medical School, Singapore
Fat tissue-derived cells can be clinically useful sources for exerting anti-diabetic actions and for producing induced pluripotent stem (iPS) cells. They have great potentials for developing personalized regenerative medicine, diagnostic and therapeutic platforms, and human disease modeling. | 10:00 | Market Analysis of Personalized Medicine and Emerging Classes of Biomarkers Enal Razvi, Managing Director, Select Biosciences Inc, United States of America
| 10:30 | Coffee and Networking in Exhibition Hall | | Session: Technologies for Molecular Diagnostics |
| | 11:15 |  | Keynote Presentation Finicky and Sloppy Molecular Beacons Fred Kramer, Professor, New Jersey Medical School, United States of America
The hairpin shape of molecular beacons enables them to be designed to be either extraordinarily specific for the direct identification of a target sequence, or to be mismatch-tolerant for the identification of a target sequence by determination of the stability of the resulting hybrid. |
| 12:15 | Technology Spotlight: DNA Sequencing on A Semi-conductor Chip: Applications in Diagnostic Testing Manohar Furtado, VP, Life Technologies Corporation
| 12:30 | Lunch and Networking in Exhibition Hall | 13:30 | Poster Viewing Session | 14:15 | Multiplexed Homogenous Proximity Extension Assays Martin Lundberg, Scientist, Olink Bioscience, United Kingdom
This presentation will describe the antibody based homogenous Proximity Extension Assay (PEA) and how it can be used for biomarker screening. Performance and promising data from a pilot biomarker study will be presented for a 96-plex panel. | 14:45 | A Pre-reverse Transcription Preheating Step for Enhancement in microRNA Detection Sensitivity by Real-time PCR Multiplex Array with Minute RNA Input Leong Mai, Scientific Officer, National University Hospital, United States of America
| 15:15 | Coffee and Networking in Exhibition Hall | 15:45 | Engineering of Nanoplasmonic Structures for the Amplification-Free Detection of Single Nucleotide Variations using Sub-diffraction Limit Imaging Musa Mhlanga, Principal Investigator, Council for Scientific and Industrial Research Biosciences, South Africa
The exquisite sensitivity of molecular beacons combined with the nanoplasmonic structures allow us to achieve amplification-free single molecule detection of DNA in sub-diffraction limit imaging regimes. | 16:15 | Epiallele Quantification Using Molecular Inversion Probes Ramkumar Palanisamy, Research Student, The University of Queensland, Australia
A multiplex assay using molecular inversion probes and DNA biosensors has been developed. The assay requires low amounts of DNA to quantitate methylations in multiple methylation sites that may provide an insight into the methylation fingerprint of DNA and cancer. | 16:45 | Close of Conference |
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