08:00 | Registration |
| Day One |
| Session Chair: Peter Loskill, Assistant Professor for Experimental Regenerative Medicine; Attract Group Leader Organ-on-a-Chip, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Eberhard Karls University Tübingen, Germany |
| |
09:00 | Biomaterials Design for Experimental Organ Models Gianluca Ciardelli, Professor, Polytechnic University of Turin, Italy
Engineered tissue models offer new options for a better understanding of disease progress and the development of new treatments. In this work biomimetic scaffolds are proposed as innovative myocardial and bone models. |
09:30 | | Keynote Presentation Multi-Organ-Chip Technologies: Towards a Paradigm Shift in Drug Development Uwe Marx, CSO & Founder, TissUse GmbH, Honorary Professor for Medical Biotechnology at the Technische Universität Berlin, Germany, Germany
The keynote summarizes latest achievements in the development of biology-inspired microfluidic microphysiological system approaches (organ-on-a-chip, body-on-a-chip). It furthermore highlights progress and challenges in industrial adoption of MPS-based approaches to address the prediction dilemma of drug testing. |
|
10:15 | Translational Applications of Microphysiological Systems (MPS) Murat Cirit, Director at Translational Center of Tissue Chip Technologies, Massachusetts Institute of Technology (MIT), United States of America
Systems pharmacology approaches to microphysiological systems (MPS) enable mechanistic data interpretation and, hence, in vitro in vivo translation (IVIVT) of pharmacokinetics, pharmacodynamics and patient specific response biomarkers. |
10:45 | Coffee & Networking in Exhibition Hall |
11:15 | Extracellular Matrix Mimetic Hydrogels of Natural Polymers for Organ-on-chip Applications Marcel Karperien, Professor, University of Twente, Netherlands
In this presentation I will describe our strategy to develop chemically defined substitutes for matrigel that can be applied in organ-on-chip models for formation of functional microtissues. |
11:45 | A New Cells-On-A-Chip Based on Vinyl Development for Real-Time Skin Monitoring Miguel Holgado Bolaños, Group Leader, Universidad Politécnica de Madrid, Spain
This talk will present a new disposable biochip based on Vinyl and PDMS that can mimic skin physiology and architecture. |
12:15 | Biomembrane-on-a-chip Yan Yan Shery Huang, Lecturer, University of Cambridge, United Kingdom
On-Chip Microvessel Platform for Cancer Invasion Studies. |
12:45 | Lunch & Networking in Exhibition Hall |
13:15 | Poster Viewing Session |
13:30 | Free Workshop Translating Customers Ideas into Microstructured Smart Polymer Parts Workshop |
14:15 | Technology Spotlight: Linking the Liver – Interconnected Microphysiological Systems David Hughes, Chief Technical Officer, CN Bio Innovations Ltd.
Interconnected microphysiological systems often feature a liver model. Research and development relating to linked gut-liver, PBMC-liver and pancreas-liver multi-organ systems will be presented. |
14:30 | | Keynote Presentation Human-Based “Body-on-a-Chip” for Drug Development Michael Shuler, Samuel B. Eckert Professor of Engineering, Cornell University, President Hesperos, Inc., United States of America
We combine human tissue constructs, microfabrication, and physiologically based pharmacokinetic models to construct multiorgan models that are self-contained, operate upto 28 days and allow direct measurement of chemical, electrical, and mechanical responses to drugs in a serum free medium |
|
15:15 | Modelling the Eye with Microfluidics Anderson Shum, Professor, Department of Mechanical Engineering; Director, Advanced Biomedical Instrumentation Centre, University of Hong Kong, Hong Kong
I will discuss our efforts in combining microfluidics and cell-culture to mimic the retinal environment of a human eye, and outline how these could facilitate the development of new surgical procedures.
|
15:45 | Coffee and Networking in Exhibition Hall |
16:15 | Advanced Cellular Models in Drug Safety Assessment - An Industry User Perspective Cristina Bertinetti-Lapatki, Lab Head Mechanistic Safety, Roche Pharma Research & Early Development, F. Hoffmann-La Roche Ltd, Switzerland
|
16:45 | Microengineered Physiological Biomimicry: Human Organs-on-chips Dan Huh, Associate Professor of Bioengineering and Wilf Family Term Endowed Chair, University of Pennsylvania, United States of America
|
17:15 | Drinks Reception in Exhibition Hall |
18:45 | End of Day One |