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SELECTBIO Conferences Exosomes and Microvesicles

Elena Aikawa's Biography

Elena Aikawa, Associate Professor of Medicine, Brigham and Women’s Hospital, Harvard Medical School

Dr. Elena Aikawa is an Associate Professor of Medicine at Harvard Medical School and a Principle Investigator at the Center for Excellence in Vascular Biology, and Director of the Vascular Biology Program at the Center for Interdisciplinary Sciences at Brigham and Women’s Hospital, Boston, MA, USA. Dr. Aikawa has played a pioneering role in the discovery of inflammation-dependent mechanisms of calcification, and in advocacy for the early imaging and treatment of calcific aortic valve disease. Her current research aim is to develop new therapies to cure calcific aortic valve stenosis, a disease that currently has no treatment except surgical valve replacement. Dr. Aikawa is a member of the National Heart, Lung, and Blood Institute (NHLBI) Working Group on Calcific Aortic Valve Stenosis and the Alliance of Investigators on Calcific Aortic Valve Disease. She is an Editorial Board Member of Arteriosclerosis, Thrombosis and Vascular Biology, PLoS ONE, Journal of Extracellular Vesicles, and Circulation Research. Dr. Aikawa has delivered over 80 keynote lectures, invited talks and cardiovascular grand rounds, and authored more than 130 manuscripts on cardiovascular pathobiology.

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The Role of Extracellular Vesicle-derived Micro-calcifications in Atherosclerotic Plaque Vulnerability

Tuesday, 24 March 2015 at 10:30

Add to Calendar ▼2015-03-24 10:30:002015-03-24 11:30:00Europe/LondonThe Role of Extracellular Vesicle-derived Micro-calcifications in Atherosclerotic Plaque

Cardiovascular calcification, a growing burden in Westernized countries, is not only a risk factor for cardiovascular events, but may itself contribute to cardiovascular risk. Research into treatment of cardiovascular calcification is lacking, as shown by clinical trials that have failed to demonstrate the reduction of calcific aortic stenosis.  Hence the need to elucidate the pathways that contribute to cardiovascular calcification and to develop new therapeutic strategies to prevent or reverse calcification has driven our research investigations. This presentation will discuss studies that have used molecular imaging methods to advance knowledge of cardiovascular calcification, focusing in particular on the alternative mechanisms of vascular calcification via the release of calcifying matrix vesicles.

Add to Calendar ▼2015-03-23 00:00:002015-03-24 00:00:00Europe/LondonExosomes and