Michael Shuler,
Samuel B. Eckert Professor of Engineering,
Cornell University, President Hesperos, Inc.
Michael L. Shuler is the Eckert Professor of Engineering, Emeritus in the Meing Department of Biomedical Engineering and in the Smith School of Chemical and Biomolecular Engineering at Cornell University, and was director of Cornell’s Nanobiotechnology Center. Shuler has degrees in chemical engineering (BS, Notre Dame, 1969 and Ph.D., Minnesota, 1973) and has been a faculty member at Cornell University since 1974. Shuler’s research includes development of “Body-on-a-Chip” for testing pharmaceuticals for toxicity and efficacy, creation of production systems for useful compounds, such as paclitaxel from plant cell cultures, and construction of whole cell models relating genome to physiology. Shuler is CEO and President of Hesperos, a company founded to implement the “Body-on-a-Chip” system. Shuler and F. Kangi have authored a popular textbook, “Bioprocess Engineering; Basic Concepts” now in its third edition. He has an honorary doctorate from the University of Notre Dame. Shuler has been elected to the National Academy of Engineering and the American Academy of Arts and Science and is a fellow of numerous professional societies.
Human “Body-on-a-Chip” Devices as Tool to Improve Drug Development
Wednesday, 28 September 2016 at 13:30
Add to Calendar ▼2016-09-26 00:00:002016-09-26 01:00:00Europe/LondonTitle to be Confirmed.Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Alternatives or supplements to the use of animals in preclinical drug
development that better mimic human response should reduce costs and
increase the number of FDA approved drugs at the end of clinical trials.
We have constructed micro-physiological (or “Body-on-a-Chip”) devices
constructed from a combination of human tissue engineered constructs,
micro-fabricated devices and physiologically based pharmacokinetic
(PBPK) models. These human surrogates are constructed on a low cost,
robust “pumpless” platform. In addition to measuring viability and
metabolic responses, we can measure functional outputs such as
electrical activity and force generation using integrated sensors (in
collaboration with J. Hickman, University of Central Florida). We will
focus our discussion on development of key organ modules and their
integration with each other to form a model of the human body.
Add to Calendar ▼2016-09-26 00:00:002016-09-28 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2016-09-26 00:00:002016-09-26 01:00:00Europe/LondonTitle to be Confirmed.Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
