Steve Blair received the B.S. and M.S. degrees in Applied Optics from Rose-Hulman Institute of Technology, Terre Haute, IN, in 1991 and 1993, respectively, and the Ph.D. degree in Electrical Engineering from the University of Colorado, Boulder, in 1998. Since 1998, he has been with the Electrical and Computer Engineering Department, University of Utah, Salt Lake City, and is now an Associate Professor. His research interests include plasmonics, microarray technology and applications, and optical methods for neural stimulation.
Plasmonic-Enhanced Single-Molecule Detection
Wednesday, 28 September 2016 at 15:30
Add to Calendar ▼2016-09-28 16:00:002016-09-28 17:00:00Europe/LondonPlasmonic-Enhanced Single-Molecule DetectionLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
The next generation of molecular diagnostics tools are targeted to have
single molecule sensitivity. Plasmonic-enhanced fluorescence can be a
key enabling factor in achieving this goal. Large-scale arrays of
plasmonic structures meet the requirements of enhanced
signal-to-background in fluorescence detection, along with compatibility
with existing instrumentation and surface chemistry. Fluorescence
enhancement results from a combination of plasmonic mediated excitation
and emission enhancement. Even though molecules are confined within a
plasmonic structure, the spectral region of enhancement depends strongly
on the metal. As such, have also been working with structures in Al,
which is mass-production friendly and provides balanced enhancement
throughout the visible spectrum, opening up a wider range of
applications. However, new chemical passivation strategies need to be
devised due to the native oxide of Al. Tuning of the relative
enhancements can be accomplished by adjusting the shape of the plasmonic
structures, opening up the UV spectral range where the native
fluorescence of biomolecules can be accessed.
Add to Calendar ▼2016-09-26 00:00:002016-09-28 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016Lab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2016-09-28 16:00:002016-09-28 17:00:00Europe/LondonPlasmonic-Enhanced Single-Molecule DetectionLab-on-a-Chip, Microfluidics and Microarrays World Congress 2016 in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
