Paul Yager,
Professor, Department of Bioengineering,
University of Washington
Paul Yager is the Professor in the Department of Bioengineering at the University of Washington, Seattle. Professor Yager served as the The Hunter and Dorothy Simpson Endowed Chair, Department of Bioengineering from 2008-2013. Professor Yager's research focuses on microfluidics and its applications in global health.
The Difficult First Step for POC Diagnostics
Monday, 7 October 2019 at 17:15
Add to Calendar ▼2019-10-07 17:15:002019-10-07 18:15:00Europe/LondonThe Difficult First Step for POC DiagnosticsSELECTBIOenquiries@selectbiosciences.com
A diagnostic process, no matter how long, begins with a first step.
Whether to guide treatment of an individual’s infection, or to control
the outbreak of a pandemic, there is an urgent need for low-cost rapid
diagnostic devices capable of identifying the cause of infectious
disease that work wherever the person is, not just in a centralized
laboratory. “Ubiquitous diagnostics” can bring the best diagnostic
capabilities to homes, physicians’ office laboratories and pharmacies in
the developed world, or to places in the developing world where nothing
is available now. However, the greatest challenge is often not
detection of the analyte(s), but the preparation for the sample for that
detection process. Samples differ in volumes, the concentration of the
analyte, and the presence of components that can interfere with analyte
detection. We have been working to develop simple devices for nucleic
acid amplification tests (NAATs) for the presence of Chlamydia and
gonorrhea, Mycobacterium tuberculosis and HIV. To enable them we have
created a suite of stand-alone or integrated sample-handling components
that can process blood, urine or swabs from different cavities in the
body: the goal in all cases is to create a few microliters of a fluid
that is both concentrated and “clean” enough that it can be introduced
automatically into a sensitive NAAT device of our own design. We will
show recent progress in reducing such processes to a few user-friendly
steps appropriate for untrained users.
Add to Calendar ▼2019-10-07 00:00:002019-10-09 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics 2019: Emerging Themes, Technologies and Applications Track "A"SELECTBIOenquiries@selectbiosciences.com