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SELECTBIO Conferences Microfluidics for Circulating Biomarkers Summit 2019

Hsian-Rong Tseng's Biography

Hsian-Rong Tseng, Professor, Crump Institute for Molecular Imaging, California NanoSystems Institute, University of California-Los Angeles

Dr. Tseng is professor in the Department of Molecular & Medical Pharmacology at UCLA. He also holds memberships of the California NanoSystems Institute, Crump Institute for Molecular Imaging and Institute for Molecular Medicine on the UCLA campus. Since he joined UCLA Pharmacology in 2003, Dr. Tseng’s group at UCLA has developed a series of nanotechnology- and microfluidics-enabled in vitro molecular diagnostic (IVMD) technologies. In collaboration with his physician colleagues, the goal of their joint team is to translate these new IVMD technologies from research bench to clinical practice.

Hsian-Rong Tseng Image

Nanostructures-Embedded Microchips for Liquid Biopsy in Cancer

Thursday, 10 October 2019 at 14:45

Add to Calendar ▼2019-10-10 14:45:002019-10-10 15:45:00Europe/LondonNanostructures-Embedded Microchips for Liquid Biopsy in CancerMicrofluidics for Circulating Biomarkers Summit 2019 in Coronado Island, CaliforniaCoronado Island,

The current gold standard for cancer diagnosis is the characterization of tumor tissues acquired via invasive procedures, e.g., surgical excision or needle biopsy. As an alternative to solid tumor biopsy, many have proposed the use of a “liquid biopsy” based on blood components like circulating tumor cells (CTCs) and extracellular vesicles (EVs). By detecting, enriching, and analyzing CTCs and EVs, we will be able to noninvasively and dynamically monitor disease progression in individual cancer patients and obtain insightful information for assessing disease status. Over the past decade, our research team at UCLA pioneered a unique concept of “NanoVelcro” CTC Chips and “NanoVilli” EV Chips, in which CTC and EV capture agent-coated nanostructured substrates were utilized to immobilize CTCs and EVs with remarkable efficiency, respectively. Multiple generations of NanoVelcro CTC and NanoVilli EV Chips have been developed over the past decade for a variety of clinical utilities, e.g., noninvasive molecular analysis for monitoring disease progression and treatment intervention.  In this presentation, I will summarize the development of the new generations of “NanoVelcro” CTC and “NanoVilli” EV Chips, and the clinical applications of these new in vitro molecular diagnostic (IVMD) devices for cancer.

Add to Calendar ▼2019-10-10 00:00:002019-10-10 00:00:00Europe/LondonMicrofluidics for Circulating Biomarkers Summit 2019Microfluidics for Circulating Biomarkers Summit 2019 in Coronado Island, CaliforniaCoronado Island,