Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences Microfluidics for Circulating Biomarkers Summit 2019

Microfluidics for Circulating Biomarkers Summit 2019 Agenda


Print Agenda

Thursday, 10 October 2019

00:00

Daniel ChiuKeynote Presentation

Title to be Confirmed.
Daniel Chiu, A. Bruce Montgomery Professor of Chemistry, University of Washington, United States of America

00:00

Title to be Confirmed.
Balaji Panchapakesan, Professor, Department of Mechanical Engineering, Worcester Polytechnic Institute (WPI), United States of America

00:00

Title to be Confirmed.
Richard Spero, CEO, Redbud Labs, United States of America

00:00

Title to be Confirmed.
Kendall Van Keuren-Jensen, Associate Professor, Translational Genomics Research Institute, United States of America

00:00

Steve SoperKeynote Presentation

Title to be Confirmed.
Steve Soper, Foundation Distinguished Professor, Director, Center of BioModular Multi-scale System for Precision Medicine, The University of Kansas, Adjunct Professor, Ulsan National Institute of Science & Technology, United States of America

00:00

Lydia SohnKeynote Presentation

Title to be Confirmed.
Lydia Sohn, Professor of Mechanical Engineering, University of California-Berkeley, United States of America

00:00

Microfluidic Cellular Engineering System For Precision Immunotherapy
Mei He, Assistant Professor, University of Kansas, United States of America

Cells as the smallest units of the material body are taking tremendous roles in maintaining human body functions. Modifying cells as the factory to produce essential biomolecules are of substantial economic and scientific interest. In addition to the production of proteins, metabolites, and enzymes, engineering and production of exosomes are emerging for developing precision immunotherapy agents and personalized medicine. We will report novel microfluidic approaches for manipulating cellular functions in producing tailored extracellular vesicles and exosomes for advancing the cancer immunotherapy.

00:00

Hsian-Rong TsengKeynote Presentation

Title to be Confirmed.
Hsian-Rong Tseng, Professor, Crump Institute for Molecular Imaging, California NanoSystems Institute, University of California-Los Angeles, United States of America

00:00

Integrated Microfluidic Devices For Enrichment and Detection of Circulating Biomarkers
Hyo-Il Jung, Professor, Yonsei University, Korea South

The precise measurement or isolation of circulating biomarkers (CB) can serve as a powerful tool for cancer prognosis, diagnosis of minimal residual disease, assessment of tumor sensitivity to anticancer drugs, and personalization of anticancer therapy. The microfluidic device has a very strong advantage in comparison with   various modalities for the enrichment and separation of the CB in that it can be operated in a continuous manner minimizing any chance of loss. Over the past decade, our group has been working on various types of microfluidic-based enrichment and detection methods for the down-stream analysis of CBs. In this talk, I will present some of new discoveries and discuss critical concerns and future directions for the research.

00:00

Hsueh-Chia ChangKeynote Presentation

Multiplex Liquid Biopsy Platform for Fractionation of Heterogeneous Vesicles and Precision Analyses of Their RNA Cargo
Hsueh-Chia Chang, Bayer Professor of Engineering, University of Notre Dame, United States of America

Extracellular RNAs in blood are promising circulating biomarkers.  However, as they can be easily degraded, extracellular RNAs must form complexes with proteins or are encapsulated by liposomes, exosomes or microvesicles to remain stable.  As a result, stable RNA biomarkers, like mRNA and miRNA, are carried by a heterogeneity of nanocarriers in blood with wide size, electrophoretic mobility and isoelectric point distributions.  Due to their different biogenesis, these carriers have specific surface proteins and are often selective in their choice of RNA cargoes.  To offer more precise quantification of the circulating RNA biomarkers, we have developed a suite of microfluidic modules that can fractionate the carriers by size, surface proteins and isoelectric point.  Size-based separation is achieved by an asymmetric nanoporous membrane whose conic pores reduce hydrodynamic resistance and vesicle fusion.  Extensive rinsing can be carried out to remove free-floating contaminating proteins like albumin.  We also developed several lysing modules that can lyse the vesicles and dissociate the complexes non-chemically, such that low-yield extraction can be eliminated as an intermediate step.  We integrate these modules with our membrane sensor, digital PCR module and nanopore sensor for RNA identification and quantification to achieve an integrated multiplexed platform for precise profiling of RNA cargoes in fractionated carriers.  Some of the upstream modules can also be integrated into a pretreatment platform for NGS.

00:00

Sehyun ShinKeynote Presentation

Title to be Confirmed.
Sehyun Shin, Professor & Director, Nano-Biofluignostic Engineering Research Center, Korea University and Anam/Guro Hospital of Korea University, Korea South


Agenda is not currently available
Add to Calendar ▼2019-10-10 00:00:002019-10-11 00:00:00Europe/LondonMicrofluidics for Circulating Biomarkers Summit 2019Microfluidics for Circulating Biomarkers Summit 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com