Jeroen Rouwkema,
Associate Professor,
University of Twente
Jeroen Rouwkema, PhD, got his PhD in Regenerative Medicine from the University of Twente, the Netherlands, in 2007. He received his PhD under the supervision of Prof. Clemens van Blitterswijk and gained further experience at MIT (Prof. Bob Langer), Keele University (Prof. Alicia El Haj) and Harvard Medical School (Prof. Ali Khademhosseini). He is currently an Associate Professor at the Department of Biomechanical Engineering, University of Twente, where he leads his own group focusing on vascularization of engineered tissues. He is a tissue engineer with an extensive experience in this field, having focused on the vascularization of skeletal muscle, bone, and cardiac muscle tissue. To optimize the organization and maturation of vascular networks, he combines tissue engineering technology with mechanical and chemical stimulation, computational modeling and biofabrication. He has received several personal scholarships, including a VENI scholarship (2011-2014), a Marie Sklodowska-Curie International Outgoing Fellowship (2014-2017) and an ERC Consolidator Grant (2017-2022). In 2017 he received the TERMIS EU Robert Brown Early Career Principal Investigator Award in recognition of his achievements.
Vascular Organization in Engineered Tissues: Tuning the Mechanical and Growth Factor Environment
Thursday, 10 September 2020 at 12:00
Add to Calendar ▼2020-09-10 12:00:002020-09-10 13:00:00Europe/LondonVascular Organization in Engineered Tissues: Tuning the Mechanical and Growth Factor EnvironmentOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Engineered tissues are interesting platforms for investigating tissue responses to changing environments including for instance changes in gravity. Additionally, they are highly suitable to test potential drug compounds. However, to achieve a physiological response, an included vascular network is often desired.
In order to achieve multiscale organized vascular networks within engineered tissues, we are developing methodologies to spatially control the organization of vascular cells within tissue analogues. A potent approach in this is to spatially control the mechanical environment, as well as the availability of angiogenic growth factors. By developing transparent ex ovo chicken chorioallantoic membrane (CAM) platforms, we are building tools to investigate the effect of perturbations on in vivo vascular development and organization. This provides us with valuable information that can be translated to an in vitro tissue engineering setting. With this approach, our aim is to locally control tissue remodeling and maturation, resulting in a vascular network that resembles a vascular tree.
Add to Calendar ▼2020-09-09 00:00:002020-09-10 00:00:00Europe/LondonOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020Organ-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2020-09-10 12:00:002020-09-10 13:00:00Europe/LondonVascular Organization in Engineered Tissues: Tuning the Mechanical and Growth Factor EnvironmentOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
