Stefano Da Sacco,
Assistant Professor of Urology, GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology,
Keck School of Medicine – University of Southern California
Dr. Stefano Da Sacco is an Assistant Professor at Keck School of Medicine, University of Southern California. Before joining the Faculty at USC he was a research fellow at University of Padova (Italy) and University of Southern California, where he obtained his PhD, and a postdoctoral fellow at Children Hospital of Los Angeles. His federally funded lab has developed a functional glomerulus-on-a-chip platform currently used to study disease mechanisms in membranous nephropathy, disease modeling and biomarker discovery. In addition, Dr. Da Sacco’s team studies human kidney development and Wilms Tumor, with a focus on the nephrogenic progenitor niche.
The Glomerulus-on-a-Chip as a Platform for Disease Modeling, Drug Screening, Biomarker Discovery and mechanistic Studies
Wednesday, 9 September 2020 at 16:00
Add to Calendar ▼2020-09-09 16:00:002020-09-09 17:00:00Europe/LondonThe Glomerulus-on-a-Chip as a Platform for Disease Modeling, Drug Screening, Biomarker Discovery and mechanistic StudiesOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Within the kidney, the glomerulus is the structure in charge of the renal ultrafiltration. Loss of glomerular function leads to renal damage and could end with irreversible damage. The major roadblocks to advancing new drugs and therapeutics designed specifically to preserve glomerular function stem from the inability to effectively develop multicellular in vitro models that can accurately mimic the architecture of the glomerular filtration barrier. We have recently developed a barrier-free, human based glomerulus-on-a-chip system that closely replicates the glomerular filtration barrier and its functions. In this session we will present our platform and discuss our newer insights on modeling of various diseases including membranous nephropathy, Alport Syndrome and diabetic nephropathy as well as describe potential applications ranging from mechanistic studies, biomarker discovery and personalized medicine.
Add to Calendar ▼2020-09-09 00:00:002020-09-10 00:00:00Europe/LondonOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020Organ-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2020-09-09 16:00:002020-09-09 17:00:00Europe/LondonThe Glomerulus-on-a-Chip as a Platform for Disease Modeling, Drug Screening, Biomarker Discovery and mechanistic StudiesOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
