Mohammad Jouybar,
Researcher,
Politecnico di Milano
Mohammad Jouybar worked as researcher in Mimic Lab and pursued his studies in Politecnico di Milano. His work was focused on design and fabrication of microfluidic devices for in-vitro studies, specifically Gut- and Lung-on-Chip. This project was in collaboration with European Institute of Oncology in Milan, where Mohammad worked one year as a research fellow. Their focus in Microbiome and antiTumor Immunity group was microbiome contribution to cancer research. He has recently joined Microsystems group in Eindhoven University of Technology (TU/e), where he started on the "Moore4Medical" project embedded in Cancer Metastasis on Chip project under supervision of Prof. den Toonder.
A Novel Soft Lithography Technique for Porous Membrane Fabrication as a Permeable Barrier in Gut- and Lung-on-Chip Devices
Thursday, 10 September 2020 at 16:00
Add to Calendar ▼2020-09-10 16:00:002020-09-10 17:00:00Europe/LondonA Novel Soft Lithography Technique for Porous Membrane Fabrication as a Permeable Barrier in Gut- and Lung-on-Chip DevicesOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
To mimic the epithelium-endothelium barrier in microfluidic devices, the fabrication of porous membranes through soft-lithography is a common option. Thus far, SU8 photoresist micropillars are the prevailing master molds. However, they suffer from the fragile behavior of pillars and need sophisticated clean room facility. In this presentation, we introduce a spin-coatable epoxy-based mold of micropillars to overcome the limitations of former techniques.
Both intestinal and lung epithelium cell lines were cultured in microchannels to validate the functionality of the porous membrane. Subsequently, to evaluate the contribution of mechanical stimulation with focus on flow, to the 3D morphogenesis of intestinal epithelium, three different culture methods were tested: pump perfusion, tilting rocker perfusion, and steady culture. The primary results will be presented in this presentation.
Add to Calendar ▼2020-09-09 00:00:002020-09-10 00:00:00Europe/LondonOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020Organ-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2020-09-10 16:00:002020-09-10 17:00:00Europe/LondonA Novel Soft Lithography Technique for Porous Membrane Fabrication as a Permeable Barrier in Gut- and Lung-on-Chip DevicesOrgan-on-a-Chip, Tissue-on-a-Chip and Organoids Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
