Cesar Pascual García,
Lead Research Scientist,
Luxembourg Institute of Science and Technology
César Pascual García is Coordinator and Principal investigator of research projects and also Core-Tech line manager at the Luxembourg Institute for Science and Technology for materials MedTech for personalized medicines. His study focuses developing lab on a chip devices to detect, synthesize, modify, and decompose the DNA and proteins using microchip technology to function alongside biology. He is currently the project coordinator for ELECTROMED, a FET-OPEN project sponsored by the European Innovation Council to build a cancer vaccine-screening platform, based on FET-sensors with programable peptide sequences. He was recently appointed as the European Innovation Council's ambassador until 2027.
A High Aspect Ratio FinFET, A Compromise to Reach Efficient Electrochemical Sensing
Wednesday, 9 October 2019 at 12:00
Add to Calendar ▼2019-10-09 12:00:002019-10-09 13:00:00Europe/LondonA High Aspect Ratio FinFET, A Compromise to Reach Efficient Electrochemical SensingPoint-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
Bio-sensing for early diagnostics and to facilitate clinical-decisions is a key-enabling technology for the implementation of next generation. In the last decades, several devices for molecular diagnostics based in the manipulation of genetic material (DNA, RNA…) have validated this concept. The next step is demanding tools for the detection of molecules beyond nucleotides. Field effect transistors (FETs) emerge as one of the candidates for label free sensing, in fact, nano-FETs have shown limits of detection in the femtomolar range. However no clinical applications are currently available. The first drawback is the balance between the optimisation for diffusion-limited processes and reliability, which has made that multiplexing for personalised medicines has low confidence levels and hampers mass production to lower the cost of Point of Care devices. The second limitation is the ionic screening in biological conditions. Many assays using label free sensing measure end-point assays after cleaning and using low ionic strength electrolytes. This decreases the relevance of the measurements and hinders the possibility to access the kinetic information of the molecular binding. We will present a new design of FET for label free sensing using a high aspect ratio FinFET that addresses appropriately all these questions.
Add to Calendar ▼2019-10-07 00:00:002019-10-09 00:00:00Europe/LondonPoint-of-Care Diagnostics, Global Health and Biosensors 2019Point-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2019-10-09 12:00:002019-10-09 13:00:00Europe/LondonA High Aspect Ratio FinFET, A Compromise to Reach Efficient Electrochemical SensingPoint-of-Care Diagnostics, Global Health and Biosensors 2019 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
