Kal Ramnarayan's Biography

Kal Ramnarayan, President and Chief Scientific Officer, Sapient Discovery

Dr. Kal Ramnarayan (Dr. Ram) is the Founder, President, Chief Scientific Officer of
Sapient Discovery. Previously, Dr. Ramnarayan Co-founded Structural Bioinformatics,
Inc and Cengent Therapeutics, Inc. As part of the senior management team, he
participated in raising more than US$ 50M. His technology leadership results in several
leads for targets like ALF, PTP1B, SHP-2, DER, TNFR, Her-2, ZAP-70, IKKB, CD45,
NY2R amongst others. He has had several successful grants from DARPA and SBIR.
He has collaborated extensively with GSK, Novartis, J and J, DuPont, several Japanese,
European and American companies in projects for lead discovery. Prior to Structural
Bioinfofmatics, Inc., Dr. Ram was Head of Computational Chemistry at
ImmunoPharmaceutics Inc., where he designed numerous drug leads, including highly
specific endothelin-A receptor antagonists. This became Sitaxsentan, currently in Phase
III clinical development by Encysive Pharmaceuticals. Dr. Ramnarayan holds a PhD in
molecular biophysics from the Indian Institute of Science, Bangalore and has multiple
papers and patents and several other patents pending. He is on the Advisory Board of
the IBM BlueGene Initiative, Strand Genomics, Polyclone Bioservices and Keck
Research Institute. He is on the Editorial Board of Current Proteomics.