Edwin van der Pol,
Assistant Professor,
Amsterdam University Medical Center
Edwin van der Pol (www.edwinvanderpol.com) is an assistant professor at the Vesicle Observation Center in the Amsterdam University Medical Centers in The Netherlands. He studied applied physics with a specialization in optics and biophysics at the University of Twente in the Netherlands. In 2009, he graduated in the Complex Photonic Systems group and at the institute for Atomic and Molecular Physics on addressing single optical resonances in micropillar cavities. In 2015, he received his PhD cum laude on the topic of extracellular vesicle detection, for which he received the PhD thesis award from the Dutch Society for Biophysics and Biomedical Engineering and the Andreas Bonn medal from the Dutch Society for the Advancement of Science, Medicine and Surgery. Edwin his current work focuses on the development of new hardware and software and standardization (www.metves.eu) in order to take extracellular vesicle diagnostics to the clinic. To make part of his inventions available to other vesicle researchers, Edwin co-founded the company Exometry (www.exometry.com).
Are Extracellular Vesicles In Liquid Biopsies the Source of My Signals?
Tuesday, 1 March 2022 at 11:30
Add to Calendar ▼2022-03-01 11:30:002022-03-01 12:30:00Europe/LondonAre Extracellular Vesicles In Liquid Biopsies the Source of My Signals?Circulating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
To discover new biomarkers in blood plasma, bulk assays are frequently applied after particle isolation. Particles of interest include extracellular vesicles (EVs), EV-associated miRNA, and circulating cell-free DNA. Blood plasma, however, is a complex body fluid that contains many other particles, such as lipoprotein particles, protein aggregates, and residual platelets, which may have similar physical properties. Therefore, isolation methods neither enrich nor recover 100% over the particles of interest. Moreover, signals of bulk assays do not necessarily originate from the particles of interest. By combining physical models with new isolation methods and a flow cytometer of which all aspects are calibrated, we gained new insights in the efficacy of methods to isolate and detect EVs and other particles in plasma.
Add to Calendar ▼2022-03-01 00:00:002022-03-02 00:00:00Europe/LondonCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022Circulating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2022-03-01 11:30:002022-03-01 12:30:00Europe/LondonAre Extracellular Vesicles In Liquid Biopsies the Source of My Signals?Circulating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
