Conferences \ Circulating Biomarkers, Exosomes & Liquid Biopsy Europe 2022 \ Agenda \ Dominique PV de Kleijn |
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Welcome and Introduction by Conference Chairperson and an Overview of the Field of Extracellular Vesicles, circa 2022Tuesday, 1 March 2022 at 09:00 Add to Calendar ▼2022-03-01 13:00:002022-03-01 14:00:00Europe/LondonPlasma Extracellular Vesicles for Cardiovascular DiseaseCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com Plasma Extracellular Vesicles for Cardiovascular DiseaseTuesday, 1 March 2022 at 13:00 Add to Calendar ▼2022-03-01 13:00:002022-03-01 14:00:00Europe/LondonPlasma Extracellular Vesicles for Cardiovascular DiseaseCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com Cardiovascular Disease (CVD) is with the cardiovascular events of Ischemic Heart Disease and Stroke, the number 1 and 2 cause of death in the world and expect to increase especially in Asia. In this presentation we use plasma extracellular vesicle (EV) protein content of vesicles from plasma subfractions on plasma of stroke and TIA patients after carotid atherectomy (CEA). AtheroExpress the large ongoing CEA biobank gives us the unique possibility to compare the different biomarker sources of EV, plasma and carotid plaque in association with onset symptoms and risk of a second Major Adverse Cardiovascular Event (MACE: myocardial infarction, stroke or cardiovascular death). We also evaluated if EV proteins could contribute to identification of patients at high risk for MACE or Major Adverse Limb Event (MALE: repeated surgery or limb amputation) after surgery in Peripheral Artery Disease (PAD) patients. Identification of such high risk patients is very important for possible (expensive) add-on pharmaceutical therapy or the decision to operate or not. |