John Naber,
Director, Flow Chemistry and Lab Automation, Process Research & Development,
Merck & Co
John leads the Flow Chemistry and Lab Automation teams within Enabling Technologies as part of Process Research & Development at MSD. The New Jersey based flow team works closely with the larger process organization to implement flow chemistry processes during late stage and commercial route development.
John began his industrial career at i2Chem a Cambridge (MA) based CRO that specialized in flow chemistry process development before moving to MSD in 2012. John received his PhD from the Massachusetts Institute of Technology in 2010 where he completed his research under the direction of Stephen L. Buchwald. During his time at MIT he was introduced to flow chemistry through the MIT-Novartis Center for Continuous Manufacturing. He holds a BSc in Chemistry from the University of Victoria in Canada.
Fast Mixing, Ketimine Additions, and the Application of Flow Chemistry to Verubecestat
Tuesday, 7 February 2017 at 17:15
Add to Calendar ▼2017-02-07 17:15:002017-02-07 18:15:00Europe/LondonFast Mixing, Ketimine Additions, and the Application of Flow Chemistry to VerubecestatFlow Chemistry Europe 2017 in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
The development of a novel method for ketimine additions enabled a key step in the synthesis of Merck Sharpe and Dohme’s (MSD) Phase III compound for Alzheimer’s disease. The production of hundreds of kilograms of material in a pilot plant campaign and the associated mixing studies at lab and plant scale are presented.
Add to Calendar ▼2017-02-07 00:00:002017-02-08 00:00:00Europe/LondonFlow Chemistry Europe 2017Flow Chemistry Europe 2017 in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com