SELECTBIO - Genomics & Proteomics Research Agenda

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Genomics & Proteomics Research Agenda

Thursday, 28 May 2015

Agenda

08:00

Registration

09:00

Inauguration

Opening Lecture

09:15

Keynote Presentation

Proteomics, High Throughput Science and India - Cancer Perspective
Ravi Sirdeshmukh, Distinguished Scientist & Associate Director , Institute of Bioinformatics

10:15

Coffee Break and Networking Session

Session 1: Genome Informatics in Drug Discovery/ Session Chair: Tapas Kundu

10:45

Keynote Presentation

Genomes to Hit Molecules In Silico: A Country Path Today, A Highway Tomorrow
B Jayaram, Professor, Indian Institute of Technology Delhi

11:30

Q/A Session

11:35

Bioinformatics Genome-Wide Survey of Myosins
Ramanathan Sowdhamini, Professor, National Centre for Biological Sciences

12:05

Q/A Session

12:10

Personal Genomes to Precision Medicine
Vinod Scaria, Scientist, Institute of Genomics and Integrative Biology

This presentation, describes the experiences with personal genome sequencing and use of genomics approaches and model systems. The talk also highlights a platforms for systematic curation of information and crowdsourcing highly specialised tasks online through CrowdOmics platform. Systematic annotation of datasets for personalised genomics for the OpenPGx consortium and analytical tasks through the 2C4C programme for Cheminformatics could be crowdsourced through the platform.The talk would also discuss the way forward, detailing the ongoing initiatives including the GUaRDIAN Consortium involving a large clinical network towards realising the dream.

12:40

Q/A Session

12:45

Poster Viewing

13:00

Lunch Break and Networking Session

Session 2: Engineering Genome for Clinical Applications/ Session Chair: Rajalakshmi Gope

14:00

Keynote Presentation

Histone Interacting Proteins in the Regulation of Chromatin Dynamics and Transcription Regulation: Implications in Disease and Differentiation
Tapas Kundu, Professor, JNCASR

This talk will discuss how multifunctional nucleolar protein NPM1 is a histone chaperone and a potent regulator of RNA pol II driven transcription is critical for both physiological and pathophysiological (oral cancer) state of human cell.

14:45

Q/A Session

14:50

Genome Engineering Overview and Applications of CRISPRs in Drug Discovery
Prasad Krishnamurthy, Lead Investigator, Syngene International Ltd

This presentation will highlight different gene editing systems, viz. ZFNs, TALENs and CRISPR-Cas9 that are currently used to generate genetically modified cell lines and animals. CRISPR-Cas9 system will be discussed in more detail along with some examples of gene knock-out cell line generation

15:20

Q/A Session

15:25

Coffee Break and Networking Session

Session 3: Genomic & Proteomic Approaches to Biomarker Discovery/ Session Chair: K P R Pramod

15:50

Integrative Genomics and Proteomics for Linking Molecular and Clinical Worlds
Rajani Kanth Vangala, Director of Research, Thrombosis Research Institute

This presentation will discuss an integrative translational research strategy which utilizes the molecular networks to reconcile the genotypes and phenotypes. This talk will also highlights the successful integration of the disease phenotypes with molecular networks to elucidate the transcriptional regulation and identification followed by validation of biomarkers in coronary artery disease. In order to enable the participatory, preventive and precision medicine, how nanotechnology is used to develop novel technology platforms from bio-specimen collection, storage to assay development will be described in this presentation.

16:20

Q/A Session

16:25

Functional Proteomics to Identify Therapeutic Targets in Cancer
Aditi Chatterjee, Faculty Scientist, Institute of Bioinformatics

16:55

Q/A Session

17:00

End of First Day of Conference

Friday, 29 May 2015

Session 4: Recent Trends in Non Coding RNA Research/ Session Chair: M V Jagannadham

09:15

An Integrated Analysis of Coding and Non Coding Small RNA in Response to Progesterone
Amit Dutt, Principal Investigator, Scientist F, Tata Memorial Centre

09:45

Q/A Session

09:50

Short Stories on Long Noncoding RNAs
Vinod Scaria, Scientist, Institute of Genomics and Integrative Biology

10:20

Q/A Session

10:25

Coffee Break and Networking Session

Session 5: Current Approaches in Genomics and Proteomics Research/ Session Chair: Rajalakshmi Gope

10:55

Keynote Presentation

Proteomic and Proteogenomic Approaches as a Platform for Investigating Human Diseases
T S Keshava Prasad, Scientist, Institute of Bioinformatics

11:40

Q/A Session

11:45

Analysis of Proteomes: Understanding Biology
Medicharla Jagannadham, Chief Scientist, Centre for Cellular and Molecular Biology

In the this talk, Strategies used for identification of proteins along with functional analysis and large scale evaluation of protein function prediction will be discussed in detail with suitable examples

12:15

Q/A Session

12:20

Genomics and Opthalmology
G Kumaramanickavel, Director of Research, Narayana Nethralaya

12:50

Q/A Session

12:55

Poster Viewing

13:10

Lunch Break and Networking Session

SESSION 6: Advanced Practices in NGS based Genomics and Proteomics/ Session Chair: Ravi Sirdeshmukh

14:00

Fast and Accurate Mapping of Short Reads from Next Generation Sequencing Platforms
Debnath Pal, Associate Professor, Indian Institute of Science

14:30

Q/A Session

14:35

Integrating Microarray, RNA-seq & Proteomics Data for Biomarker Discovery & Network Analysis
Kshitish Acharya, Faculty Scientist, Institute of Bioinformatics & Applied Biotechnology

15:05

Q/A Session

15:10

Coffee Break and Networking Session

15:40

Keynote Presentation

The Identification of a Long Stress-Induced Non-Coding Transcript which has Increased Expression in Breast and Ovarian Cancers
David Smith, Professor, Mayo Clinic

16:40

Q/A Session

16:45

Poster Award Presentation & Vote of Thanks

17:00

End of Conference