B Jayaram

Professor, Indian Institute of Technology Delhi

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Dr. Jayaram has pursued Ph.D. from City University of New York, USA in (1982-1986); Post Doctoral Fellow (1987-88), Columbia University, USA; Senior Research Associate(1989-90), Wesleyan University, USA. He was the Faculty of the Department of Chemistry, IIT Delhi since 1990. He is a Recipient of Chemical Research Society of India Medal (2000) & IBM Faculty Award (2014). He is a Principal Investigator & Coordinator of the Supercomputing Facility for Bioinformatics & Computational Biology (SCFBio), IIT Delhi (Since 2001). SCFBio has been upgraded to a Centre of Excellence of BTIS Network of the Department of Biotechnology (DBT), Govt. of India, with effect from Dec., 2013.
He is the Member of the National Task Force on Bioinformatics of DBT (till 2009 & from 2013-2015); Programme Advisory Committee (PAC) of the Department of Science & Technology (DST), Govt. of India, for Physical Chemistry (2004 -2007); Organic Chemistry (2007-2011) and Biophysics, Biochemistry & Molecular Biology (2012-2015); FIST Committee of DST for Chemical Sciences (2009-2011); National Committee of IUPAB (2008-2011); Editorial Board of Journal of Molecular Graphics & Modeling (2009-2011).
Dr. Jayaram was a Vice President of Indian Biophysical Society (2006-2008). He was also a Head, Department of Chemistry, IIT Delhi (Sept. 2006- Aug. 2009); Founder Coordinator, Kusuma School of Biological Sciences, IIT Delhi (2008-2014); Chairman, DBT’s committee on promotion and popularization of Biotechnology (2009-2014).
He Guided several PhDs (15 completed, 10 in progress); published and presented over 100 papers in national/international journals & conferences.
He is Responsible (a) for developing Chemgenome, Bhageerath & Sanjeevini methods & softwares for genome annotation, protein tertiary structure prediction & computer aided drug design respectively, (b) for setting up a multi-teraflop supercomputing facility for Bioinformatics & Computational Biology at IIT Delhi, and (c) for making the hardware and software freely accessible at (www.scfbio-iitd.res.in) to the global user community.
He is a Faculty Facilitator/Founder Director for two start-up companies (Leadinvent & Novoinformatics) formed by students/project personnel of SCFBio, IIT Delhi.

 

Tapas Kundu

Professor, JNCASR

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Prof Tapas K. Kundu was awarded his PhD from the Indian Institute of Science, Bangalore, in the year 1995. Following his PhD, he had a short stint as a visiting foreign research associate in the National Institute of Genetics, Mishima, Japan, followed by a post-doctoral fellowship at the Rockefeller University, USA (1996-99). He joined JNCASR as in 1999. Prof. Kundu has made outstanding contributions in the area of regulation of gene expression and its link to disease and therapeutics. He is not only elucidating the mechanisms of transcription regulation through the epigenetic modifications, but also targeting them to design new generation diagnostics, as well as therapeutics. Over the years, he has published several research papers in many international journals. Several patent applications from the laboratory have been granted and some are under process, which includes several academically important research reagents with potential commercial values, some of which have already been commercialized by renowned companies. He is the recipient of several awards, noteworthy among which are: the Shanti Swarup Bhatnagar prize from CSIR (2005), the National Academy of Science, India- Reliance Industries Platinum Jubilee Award (2008), the Sir JC Bose National Fellowship from DST (2010), the GD Birla award for scientific research (2011) and more recently “The Ranbaxy Research Award 2011 in the field of Medical Sciences – Basic Research” and “India Innovation Award 2012” given by Merck Millipore 2012 (First place). He is the fellow of three major national academies of India and an editorial board member of the Journal of Biological Chemistry (JBC). Besides fundamental research, Prof. Kundu is also involved in teaching and organizing science outreach programs. His popular lectures on ‘Genes, Disease and Therapeutics’ have benefitted high school and college students greatly.

 

T S Keshava Prasad

Scientist, Institute of Bioinformatics

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Dr. T. S. Keshava Prasad is a recipient of Young Investigator Award from the Department of Biotechnology, Government of India. He is leading IOB's efforts on the development of the Human Protein Reference Database, which is cited over 2000 times. In addition, he has successfully completed a DBT funded research project on proteomic profiling of esophageal squamous cell carcinoma in collaboration with Kidwai Memorial Institute of Oncology, Bangalore. His research group is now increasingly focusing on infectious diseases, human pathogens and vectors of human diseases. He is funded by DST, Government of India to develop an epitope based diagnostic gadget for the detection of tuberculosis in Indian population. He is using genomic and proteomic strategies to investigate biomarkers for infectious diseases including tuberculosis and malaria; and to identify molecules associated with host responses to infections in different chronic meningitis cases. Using proteogenomic principles, he is carrying out genome annotation of infectious fungi including species of Candida and Cryptococcus; and vector mosquitoes such as Anopheles stephensi and Aedes aegypti. Recently, he has received the F1000 travel award from the Wellcome Trust to present the proteogenomic data of An. stephensi in the “EMBO international conference of Molecular and Population Biology of Mosquitoes” held at Kolymbari in Greece. He is an editorial board member for the Journal of Proteomics and Bioinformatics and a reviewer for the journals Molecular and Cellular Proteomics, PLOS One, Journal of Proteomics, Proteomics, Trends in Molecular Medicine, Genomics, BMC Bioinformatics, Bioinformatics, BBA - Proteins and Proteomics, DNA Research, International Journal of Molecular Sciences and Bioinformatics and Biology Insights.

 

Ravi Sirdeshmukh

Distinguished Scientist & Associate Director , Institute of Bioinformatics

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Dr. Ravi Sirdeshmukh obtained his Ph.D. in Biochemistry from the Centre for Cellular and Molecular Biology (CCMB), Hyderabad - a premier national laboratory where he later joined as a Senior Scientist. He also worked as a Visiting Associate at the Washington University Medical School in St Louis, Missouri, USA and as a Visiting Scientist at the National Institutes of Health in Bethesda, USA. At the CCMB, he was holding the position of Director-Grade Scientist and heading the Proteomics Laboratory before joining the Institute of Bioinformatics as Distinguished Scientist. His research interests span the areas of protein and nucleic acid biochemistry and his earlier work included RNA processing, mRNA stability, structure- function relationship of proteins and their regulation. His more recent interests have been in the areas of proteomics of gliomas - a major class of brain tumors, proteomics of Aspergillosis and stem cell proteomics. At the CCMB, he was the nodal scientist in CSIR network programs in proteomics and also served as the Consortium Manager in CSIR Proteomics Network for International Collaborations. He is also associated with some of the international research initiatives in proteomics such as Membrane Proteomics Initiative. He is an expert reviewer for several international proteomics journals, a member of the Editorial Board of the International Journal of Proteomics and Bioinformatics and serves on the research advisory panels of some of the national Institutes in India and that of US Pharmacopea for protein therapeutics. He is an elected member of the Council of Asian Oceanean Human Proteome Organization (AOHUPO). Ravi Sirdeshmukh has played an important role in educational activities in proteomics in India and has delivered a large number of invited lectures at the University Centres, Research Institutes, coordinated training workshops, organized international Proteomics Conferences and discussions. He is the Founder President of the Proteomics Society, India which is strongly dedicated to proteomics education. He has trained and mentored a number of young associates, Ph.D. students and Postdoctoral fellows. At IOB, he plans to pursue cancer proteomics and promote translational research programs.

 

David Smith

Professor, Mayo Clinic

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David I Smith is a Professor and Consultant in the Department of Laboratory Medicine and Pathology at the Mayo Clinic where he’s been for the past 19 years. He received his Bachelors degree from the University of Wisconsin, Madison in Mathematics and Molecular Biology in 1974 and his Ph.D. also at U.W. Madison in the Department of Biochemistry in 1978. He had postdoctoral training at the Albert Einstein College of Medicine and at the University of California, Irvine, before joining the faculty at Wayne State University in Detroit in the Department of Molecular Biology and Genetics where he was for 11 years. In 1995 in joined the Mayo Clinic. His laboratory works on studying the molecular alterations that underlie cancer development and he also studies the role that the common fragile sites play in cancer development. He is also the Chairman of the Technology Assessment Group for the Center for Individualized Medicine of the Mayo Clinic and is responsible for evaluating new technologies that could have a dramatic impact on research and its clinical translation. The most exciting technology with tremendous potential to transform both research and clinical practice is next generation sequencing and Dr. Smith has been using this powerful technology to study the role that human papillomavirus plays in the development of a number of different cancers.