Acetylated Histone H2A.Z is a Key Feature of Enhancers and the Promoters of Both Active and Bivalent Genes in Mouse ESCs

Wednesday, 5 September 2012 at 11:45

Add to Calendar ▼2012-09-05 11:45:002012-09-05 12:45:00Europe/LondonAcetylated Histone H2A.Z is a Key Feature of Enhancers and the Promoters of Both Active and Bivalent Genes in Mouse ESCsSELECTBIOenquiries@selectbiosciences.com

The epigenetic landscape of the histone variant H2A.Z, both acetylated and non-acetylated, is determined in mouse ESCs using ChIP-Seq.  AcH2A.Z is present at the promoters of both active and poised (bivalent) genes and correlates with histone H3K4me3.

Colyn Crane-Robinson, Professor, University of Portsmouth

Colyn Crane-Robinson

Emeritus Professor of Biochemistry at the University of Portsmouth, UK, who has been involved in structure/function relationships of histones since the mid-sixties. Initiator in 1988 of chromatin immuno-precipitation techniques using antibodies to acetylated histones and a continuing advocate of this approach to establishing the epigenetic landscape of cells.