Wu Jie,
Associate Professor, Chemistry Department,
National University of Singapore
Jie obtained his PhD in 2012 with Prof. James S. Panek at Boston University working on natural product total synthesis. In his postdoc research at MIT with Prof. Timothy Jamison and Prof. Alan Hatton, Jie has been exposed to the hard core of continuous flow chemistry. Since joining NUS in July 2015, his research group focuses on new synthetic methodology development using photocatalysis assisted by advanced flow technologies. His group is also interested in the development of advanced flow technologies for on-demand and automated synthesis of functionalized organic molecules. In July 2021, Jie was promoted to tenured associate professor. His research group has published more than 100 papers in these research areas, with more than 10 filed patents. Jie is a recipient of Dean’s Chair Professor (2023), Tokyo Chemical Industry-SNIC Industry Award in Synthetic Chemistry (2021), NUS Young Research Award (2021), Yong Scientist Award (2020), Asian Core Program Lectureship Award (2017-2022), Thieme Chemistry Journal Award (2019), and NUS Chemistry Department Young Chemist Award (2018).
Visible-Light-Driven Fine Chemical Synthesis Using Inexpensive Natural Gases as Feedstocks in Micro-Tubing Reactors
Friday, 15 November 2019 at 12:30
Add to Calendar ▼2019-11-15 12:30:002019-11-15 13:30:00Europe/LondonVisible-Light-Driven Fine Chemical Synthesis Using Inexpensive Natural Gases as Feedstocks in Micro-Tubing ReactorsFlow Chemistry Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com
Natural gases such as CO2, ethylene, acetylene, methane, ethane are inexpensive and available in virtually unlimited amounts, making them appealing candidates as C1 and C2 feedstocks for sustainable chemical synthesis. However, any attempt at using natural gases as raw materials in synthetic endeavors has to cope with serious challenges, including the inert reactivity and difficulty of operation. Photocatalysis has witnessed dramatic developments over the past decade which provides enormous opportunities for new catalytic synthetic methodology development using natural gases. In conventional batch reactors, scalability of photo-reactions is hampered due to the attenuation effect of photon transport, which prevents the use of a dimension-enlarging strategy for scale-up. The use of continuous-flow micro-tubing reactors for photochemical applications allows these issues to be overcome, by ensuring uniform irradiation of the entire reaction mixture and scaling-up of photochemical reactions via scaling-out or numbering-up strategies. In this context, my research group at NUS has invented a “stop-flow” micro-tubing (SFMT) reactor platform, which represents an ideal laboratory bench model for reaction discover applications. Assisted by SFMT reactors, we developed methodologies to convert acetylene, CO2, ethylene, and ethane into fine chemicals. Gram-scale synthesis can be easily achieved by the SFMT reactors, and the reaction can be further scale-up by using continuous-flow technology.
