Flow Chemistry Asia Agenda

Registration

Coffee Break and Networking in Exhibition Hall

Continuous Manufacturing – Hardware and Application Processes
Olaf Stange, Researcher, Bayer Technology Services, Singapore

Flow Chemistry on the basis of process intensification or continuous manufacturing, has become an important topic in the fields of chemical and pharmaceutical industry. The presentation will illustrate the development in hardware and application processes.

Development of Continuous Crystallisation for Particle Control
Thomas McGlone, Research Fellow, University of Strathclyde, United Kingdom

There is increasing interest in exploiting the advantages of continuous crystallisation in the manufacturing of pharmaceuticals to provide reproducible, precise control over key product attributes. This presentation will highlight work being carried out within the UK EPSRC Centre for Innovative Manufacturing for Continuous Manufacturing and Crystallisation (CMAC, www.cmac.ac.uk<http://www.cmac.ac.uk>) to develop continuous crystallisation processes for control of purity, yield, crystal form, morphology and particle size.

Lunch Break and Networking in Exhibition Hall

Poster Viewing Session

Microfluidic Extraction of Metal Ions from a Complex Mineral Leach Solution
Craig Priest, Deputy Director, University of South Australia, Australia

Stream-based microfluidic solvent extraction of metal ions from complex industrial-grade leach solutions will be discussed in the context of mineral processing. The influence of fine particles and surface active reagents are evaluated, along with the path towards commercial throughput.

Microfluidic Factories for Advanced Functional Materials
Saif Khan, Associate Professor, Chemical and Biomolecular Engineering, National University of Singapore, Singapore

In this talk I will discuss the design and development of microfluidics-based flow processes for exquisitely controlled fabrication of nano- and micro-structured functional materials. 

Coffee Break and Networking in the Exhibition Hall

Capturing Fast Organometallic Transformations in Microfluidics Devices
Marc Garland, Principal Scientist II, Institute of Chemical and Engineering Sciences (ICES), Singapore

Many organometallic transformations are very fast at room temperatures. This talk explains the combined use of a microfluidics device, Raman mapping and BTEM analysis better understand these transformations.

Microfluidic Flow Cells for Process Optimization in Enzyme Assisted Synthesis
Claudia Gärtner, CEO, microfluidic ChipShop GmbH, Germany

The use of enzyme or cell cultures for the synthesis of special chemicals is an interesting field, in particular since they offer unique features for the synthesis of chirale components. To optimize such processes special conditions needs to be ensured and methods for process control should be implemented. Microfluidic systems are challenging tools to set-up and optimize enzyme based processes. Respective microfluidic modules and application data will be presented.

End of Day One

Thermochemical, Photochemical and Electrochemical Synthesis Under Flow
David Harrowven, Professor, University of Southampton, United Kingdom

The Southampton Flow Chemistry Team focuses its effort on ‘reagentless’ transformations – particularly reactions triggered by heat, light and electricity.  Herein an overview of our work is presented including reaction optimization and discovery, mechanistic studies and applications in target synthesis.

Implementation of Flow Chemistry in Exploratory Drug Development
Bryan Li, Associate Research Fellow, Pfizer Pharmaceutical Science, United States of America

The application of flow chemistry in early stage drug development of various programs will be discussed. A fit-for-purpose approach is taken to address reaction safety issues and mitigate scale up risks.

Coffee Break and Networking in the Exhibition Hall

Development of a Sustainable Phase Transfer Catalysed Continuous Process for a Pharmaceutical Intermediate
Soo Khean Teoh, Team Leader, Scientist II, Institute of Chemical and Engineering Sciences (ICES), Singapore

Evaluation of the synergetic sustainability benefits of operating a phase transfer catalyzed process in a continuous flow system compared to a batch process at scale.

Continuous Flow Processing of RAFT Polymers
Christian Hornung, Research Group Leader, CSIRO, Australia

We developed a series of continuous flow processes for the synthesis and subsequent on-processing of RAFT polymers, using tubular reactor systems. This process provides a facile alternative scale-up route to conventional batch polymerisation.

Lunch Break and Networking in Exhibition Hall

Poster Viewing Session

Coffee, Networking and Close of Conference