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SELECTBIO Conferences Advances in NGS - Virtual Event

Advances in NGS - Virtual Event Agenda

Print Agenda

Tuesday, 5 May 2015

Please note all times are listed in EST


Setting up a scalable Bioinformatics Infrastructure for high-throughput biology
Sven Nahnsen, Head, University of Tuebingen, Germany

I will present recent developments and novel methods to overcome the demanding tasks for data and project management in NGS projects. Furthermore my talk will present production-scale implementations of bioinformatics workflows for (gen)omics data processing and analysis. Finally, I will present our solution towards a an digital, collaborative research environment allowing the integration of infrastructure, bioinformatics tools and (meta)data.


Mark CaulfieldKeynote Presentation

The 100,000 Whole Genome Sequencing Project
Mark Caulfield, Chief Scientist, Queen Mary University of London, United Kingdom

The National Health Service has recognised the transformative potential for healthcare of the genetic variation within our DNA. The sequencing of 100,000 whole genomes from people with rare disease, cancer and infectious disease linked into their electronic medical records is designed to create a life course refreshable dataset that will transform the capability and capacity to apply Genomic Medicine in patient care. This will provide new opportunities for diagnosis and prime new therapeutic advances. It may produce new uses for old medicines and enable us to stratify patient response, getting the right treatment to the right patient offering opportunities for those afflicted by diseases which disable and shorten lives.


Next Generation Sequencing for the Clinical Management of Patients with Oropharyngeal Squamous Cell Carcinoma
David Smith, Professor, Mayo Clinic, United States of America

We will describe how next generation sequencing will be transforming the clinical management of patients that have oropharyngeal squamous cell carcinoma (cancer of the base of the tongue, tonsils or larynx


Using Next Generation Sequencing to Understand Pseudomonas Syringae Pv Actinidae, an Emerging Bacterial Pathogen of Kiwifruit
Iain Lamont, Professor, University of Otago, New Zealand

This presentation will cover the application of next generation sequencing technologies in understanding the spread and physiology of Pseudomonas syringae pv actinidae, a bacterial pathogen that infects kiwifruit plants and has had major effects on the kiwifruit industry.


Advancements in Next Generation Sequencing - an Unbiased View
Shawn Baker, Chief Science Officer/Chief Executive Officer, AllSeq Inc, United States of America

AllSeq’s Sequencing Marketplace offers a unique and unbiased look at what’s going on in next generation sequencing, with insights into the popularity and true cost of the various platforms and applications. An overview of the latest trends will be presented.


The Bru-seq Technology Platform for Nascent RNA analysis
Mats Ljungman, Professor, University of Michigan, United States of America

I will present a set of novel techniques to analyze many aspects of gene expression based on the capturing of nascent RNA. I will show examples of how this platform of techniques allow for the analyses of synthesis and degradation of RNA, splicing kinetics, transcription elongation rates and mapping of active enhancer elements genome-wide in human cells.

Wednesday, 6 May 2015

Please note all times are listed in EST


Bioinformatics predictions and Ion Torrent PGM RNA-seq evidence of intrinsic transcriptional terminators in Neisseria gonorrhoeae
Lori Snyder, Reader, Kingston University, United Kingdom

All inverted repeat DNA uptake sequences in the genome predicted by bioinformatics to be intrinsic terminators were investigated by RNA-seq for transcriptional termination.


Cronobacter, the Emergent Bacterial Pathogen Enterobacter Sakazakii Comes of Age
Stephen Forsythe, Professor, Nottingham Trent University, United Kingdom

The application of NGS to the emergent bacterial pathogen associated with infant meningitis will be reviewed, demonstrating the rapid characterisation, improved understanding which have been achieved, and the contribution to control of the bacterium as recommended by the World Health Organization (WHO).


Clinical Applications of Molecular Profiling for Cancer Therapy
Ramesh Ramanathan, Medical Oncologist, Translational Genomics Research Institute, United States of America

This presentation will cover advanced metastatic cancer responding to therapy and chemotherapy; biomarkers and their relevance to cancer therapies; the challenges in clinical practice to identify biomarkers for targeted therapy. Clinical trials of targeted agents and ways to accelerate cancer drug development will also be discussed.


A Case for RNAseq in Prostate Cancer Research
Melanie Lehman, Research Scientist, Queensland University of Technology, Australia

This presentation will discuss the collaborative efforts by a Movember funded multidisplinary team of researchers in Australia, Canada and Ireland to use RNAseq data to investigate treatment resistance in advanced prostate cancer.


Michael MetzkerKeynote Presentation

New Frontiers – NGS Applications in Early Human Health and Diagnostics
Michael Metzker, President & Chief Executive Officer/Adjunct Associate Professor, Baylor College of Medicine, United States of America

Advances in next-generation sequencing technologies are driving transformation into clinical practice with accessible, comprehensive, and non-invasive diagnostic tests.  Translation of these advances is most evident in the areas of prenatal and cancer diagnostics.

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